Vascular dementia (VaD) is a group of heterogeneous diseases with the common feature of cerebral hypoperfusion. To identify key factors contributing to VaD pathophysiology, we performed a detailed comparison of Wistar and Sprague-Dawley (SD) rats subjected to permanent bilateral common carotid artery occlusion (BCCAo). Eight-week old male Wistar and SD rats underwent BCCAo, followed by a refere...

AIM To use the antioxidant compounds (sodium selenite, selenomethionine, D-pantethine) for modulation of cytotoxic effect of doxorubicin and cisplatin toward wild type and drug-resistant mutants of several human tumor cells. Similar treatments were applied in vivo toward adult male Wistar rats. METHODS Human tumor cells of different lines (HCT-116, Jurkat and HL-60) with various mechanisms of...

The prevalence of type 2 diabetes mellitus (T2DM) and hypertension has markedly increased worldwide. The purpose of the present study was to examine the effects of a high-salt intake on the systolic blood pressure (SBP) and vascular responses in WBN/Kob-Leprfa/fa (WBKDF) rats, a new spontaneous animal model of T2DM. Male WBKDF rats and age-matched Wistar rats at 6 weeks of age were each divided...

background: the purpose of the present study was to investigate the effect of endurance training on amount of nicotinic acetylcholine receptors (nachr) in fast and slow twitch muscles of male wistar rats. methods: a number of 15 male wistar rats randomly divided into two groups of control (n=7) and endurance training (n=8). the endurance training treadmill running (for 12 consecutive week, 5 da...

In Indonesia illegal traditional liquor mostly contain ethanol and methanol some of called cukrik (mixed liquor), Misuse mixed can lead to intoxication may death. Several studies have shown its effect on kidney damage. This study is analyzing the (ethanol methanol) histopathological damage male Wistar rat kidney. was experimental laboratories using a post-test only control group design. We are ...

The purpose of this study was to determine the effect pineapple extract (Ananas comosus (L.) Merr.) on haematological profile male wistar rats. This type research is an experiment with a completely randomised design consisting 4 treatments 5 replications, so that 20 experimental units are obtained. variance test 95% significance level used analyse data, followed by least significant difference ...

pheromones in many vertebrates. Pheromones have been found in saliva, skin gland secretions, and urine. For example, pheromones in the urine excreted from male and female rats induce various changes in gonadal function and endocrine state, including reflex ovulation in the absence of coitus and mounting, and a reduction in the oestrous cycle of female rats from 5 to 4 d, and oestrous synchrony ...

objective:  anchomanes difformis is a member of the plant family araceae which is used as a diuretic but also has other medicinal applications. this study investigates the dietary effects of a. difformis on the kidneys of adult wistar rats. materials and methods: sixteen rats were used and were weighed, before and after the experiment. all rats were randomly divided into four groups. all groups...

OBJECTIVE The objective of this study was to observe the effect of maternal deprivation on somatic growth of wistar rat pups viz. Body weight, nose-rump length, tail length and head length. MATERIALS AND METHOD 5 days old 50 rat pups were studied dividing equally into control and experimental groups. Experimental group (N=25) of rats were maternally deprived 1-4 hours twice daily till the wea...

OBJECTIVE The aim of this study is to compare micro-sutures commonly used in our midst. METHODS In this double-blind study, 30 Wistar rats were operated randomly divided into three groups matched according to the suture used (Nylon 10-0, 75micron, brands Microsuture((r)), Polysuture((r)) and Ethicon((r))). We analyzed the number of surgical nodes required, bleeding, surgical time and histolog...