QUESTION Several men with psoriatic arthritis have asked whether the methotrexate they take for rheumatoid arthritis will affect their fertility or the outcome of any of their partners' future pregnancies. What is known regarding risks to fertility and to fetuses? ANSWER To date, there are no reports of adverse pregnancy outcomes among men exposed to methotrexate before conception. Opinions i...

There is experimental evidence of adverse effects of endosulfan on the male reproductive system, but there are no human data. Therefore, we undertook a study to examine the relationship between environmental endosulfan exposure and reproductive development in male children and adolescents. The study population was composed of 117 male schoolchildren (10-19 years of age) of a village situated at...

The male effect refers to the effect of the introduction of the male on the oestrus cycle of the seasonally anoestrus female. This effect is a neuro-hormonal response that is utilised by flock managers to improve the ovulation rate in females and shorten the breeding season. The introduction of males to the female flock will elicit this response but the use of vasectomised males is a common pra...

Varicocele is the most common cause of male infertility and is generally correctable or at least improvable by various surgical and radiologic techniques. Therefore, it seems simple and reasonable that varicocele should be treated in infertile men with varicocele. However, the role of varicocele repair for the treatment of subfertile men has been questioned during the past decades. Although var...