In the era of (pre) elimination setting, the prevalence of malaria has been decreasing in most of the previously endemic areas. Therefore, effective cost- and time-saving validated pooling strategy is needed for detection of malaria in low transmission settings. In this study, optimal pooling numbers and lowest detection limit were assessed using known density samples prepared systematically, f...

background : plasmodium falciparum infection is endemic in most tropical countries and will definitely infect human immunodeficiency virus (hiv) positive patients living in this region at one time or the other during the course of their infection. this study was conducted to determine the prevalence of malaria infection in hiv-infected patients on highly active antiretroviral therapy in benin c...

Wild great apes are widely infected with a number of malaria parasites (Plasmodium spp.). Yet, nothing is known about the biology of these infections in the wild. Using faecal samples collected from wild chimpanzees, we investigated the effect of age on Plasmodium spp. detection rates. The data show a strong association between age and malaria parasite positivity, with significantly lower detec...

background: this study investigated the association between pfcrt, t76 allele and chloroquine resistance in patients with falciparum malaria. molecular assays for point mutations on drugs resistance-related genes are applied tools for monitoring emerging resistance and surveillance malaria control strategies in endemic areas. the mutant genotype at codon 76 of plasmodium falciparum chloroquine ...

New diagnostic tests are needed to facilitate the diagnosis of Plasmodium falciparum malaria in the returned traveler. We performed a blinded evaluation of a nonisotopic colorimetric PCR-based assay (Digene SHARP Signal System) and compared the results with those obtained by microscopy and nested PCR for the detection of P. falciparum malaria in 150 febrile travelers. By using nested PCR as the...

malaria has always been regarded as one of the most important health problems with which iran is faced. most parts of the country, especially densely populated areas, were known as malarious areas. records of 1947 show that 25% of cases referred to health centers and dispensaries of the ministry of health were due to malaria in khuzestan and caspian sea areas. the mortality rate of malaria in t...

Malaria and dengue are vector borne diseases with shared endemic profiles symptoms. This study aimed at investigating through the prevalence of malaria-dengue co-infection in febrile patients to assess level knowledge about fever among healthcare workers Bangangté. A cross-sectional was conducted from January June 2021 five facilities Cameroon. diagnosis performed by rapid tests thick smears, v...

Malaria is a life-threatening parasitic disease transmitted to humans by infected female Anopheles mosquitoes. Early and accurate diagnosis crucial reduce the high mortality rate of disease, especially in eastern Indonesia, where limited health facilities resources contribute effortless spread disease. In rural areas, lack trained parasitologists presents significant challenge. To address this ...

Background: According to World Health Organization, about 260 million people worldwide are infected with malaria and 1.5-2.7 million patients die annually. It is also a major problem in India. Prompt and accurate diagnosis of malaria is the key to prevent disease morbidity and mortality. Design of the study: Blood samples were collected from 188 individuals having history of malaria/suspected w...

Successful diagnosis, screening, and elimination of malaria critically depend on rapid and sensitive detection of this dangerous infection, preferably transdermally and without sophisticated reagents or blood drawing. Such diagnostic methods are not currently available. Here we show that the high optical absorbance and nanosize of endogenous heme nanoparticles called "hemozoin," a unique compon...