Helicobacter pylori has been strongly associated with gastritis, gastric and duodenal ulcers, and it is a risk factor for gastric cancer. Two major virulence factors of H. pylori have been described: the cytotoxin-associated gene product (cagA) and the vacuolating toxin (vacA). Since considerable geographic diversity in the prevalence of H. pylori virulence factors has been reported, the aim of...

Primary motor (M1) and secondary somatosensory (S2) cortices, although anatomically and functionally distinct, share an intriguing cellular component: corticospinal neurons (CSP) in layer 5B. Here, we investigated the long-range circuits of CSPs in mouse forelimb-M1 and S2. We found that interareal projections (S2 → M1 and M1 → S2) monosynaptically excited pyramidal neurons across multiple laye...

BACKGROUND Heart failure with preserved ejection fraction (HFPEF) is the most common form of heart failure (HF), its diagnosis being a challenge to the outpatient clinic practice. OBJECTIVE To describe and compare two strategies derived from algorithms of the European Society of Cardiology Diastology Guidelines for the diagnosis of HFPEF. METHODS Cross-sectional study with 166 consecutive a...

in this research, effects of subsurface drip irrigation method on soil and tomato yield was investigated under different salinities and two irrigation management strategies: m1= alternating irrigation with fresh water and saline water, and m2= saline water in the first half of each irrigation event and fresh water in the second half. the experiment was conducted in 320 m2 area including 30 plot...

AIM To evaluate the association between virulence factor status and antibiotic resistance in Helicobacter pylori (H. pylori)-infected patients in Ireland. METHODS DNA was extracted from antral and corpus biopsies obtained from 165 H. pylori-infected patients. Genotyping for clarithromycin and fluoroquinolone-mediating mutations was performed using the Genotype HelicoDR assay. cagA and vacA ge...

In this research, the effects of irrigation with saline and fresh water through drip irrigation method and using two irrigation management strategies: M1, M2 (M1 is irrigation with fresh water in alternative with saline water, M2 is saline water in first half time of each irrigation event and fresh water in the second half), on the yield, water productivity (WP), soil salinity, plant height...