The in vitro activity of a new triazole R126638 against Malassezia yeasts was compared with that of ketoconazole. With the agar dilution technique, minimal inhibitory concentrations were lower for R126638 compared with ketoconazole against Malassezia globosa, M. obtusa, M. slooffiae, M. restricta and two strains of M. sympodialis. On human stratum corneum in vitro, both R126638 and ketoconazole...

BACKGROUND AND OBJECTIVE Seborrheic dermatitis (SD) is a frequent disorder of the skin that is distinguished by the development of erythematous patches and yellow-gray scales. It is a multifactor disease that requires predisposing factors for its progress. Presence of these factors leads to reproduction of opportunistic yeast Malassezia spp. The aim of the present study was to isolate and ident...

BACKGROUND Malassezia species normally colonize the skin but they can change their saprophytic state and invade the stratum corneum as pathogens. AIMS To determine the prevalence of Malassezia species isolated from patients with pityriasis versicolor (PV) and to analyse their distribution according to the location of the lesion on the body. METHODS This study included 218 patients with PV a...

Malassezia folliculitis [MF] is caused by the invasion of hair follicles by large numbers of Malassezia cells, but it remains unclear which Malassezia species are involved in the disease. To clarify this situation, Malassezia species isolated from lesions of MF patients were analyzed by both culture and non-culture methods. In addition, Malassezia species recovered from the non-lesion areas of ...

There are differences with respect to the commonly isolated Malassezia species, not only between healthy individuals and the patients with various skin diseases, but also between different countries. We investigated the species composition of Malassezia microflora on the skin of patients with Malassezia-associated diseases and of healthy subjects (HS). Two hundred and fifty skin scrapings from ...

the genus malasezia currently includes fourteen species that have been isolated from healthy and diseased human and animal skin. however, there were differences with respect to the species most commonly isolated, not only in patients with various skin diseases but also between healthy individuals. the aim of this study was to analyze the prevalence of malassezia species from clinically normal s...

Although the fungal microbiome in human skin mainly comprises lipophilic yeasts, including Malassezia species, these microorganisms can cause various dermatitis conditions, pityriasis versicolor, seborrheic dermatitis, folliculitis, and atopic depending on host condition. Both globosa restricta are major species implicated Malassezia-related dermatitis. However, pathogenicity of has not been re...

BACKGROUND Most studies describing the human gut microbiome in healthy and diseased states have emphasized the bacterial component, but the fungal microbiome (i.e., the mycobiome) is beginning to gain recognition as a fundamental part of our microbiome. To date, human gut mycobiome studies have primarily been disease centric or in small cohorts of healthy individuals. To contribute to existing ...

Dandruff adalah kondisi non-inflamasi yang ditandai dengan sisik putih hingga kekuningan terkelupas pada kulit kepala. dapat disebabkan oleh faktor mikroba maupun non-mikroba. Malassezia genus jamur flora normal manusia dan sekaligus menjadi agen etiologi dandruff. Ada beberapa risiko mempengaruhi adanya dandruff, seperti perawatan rambut penggunaan hijab. Penelitian ini bertujuan untuk mengeta...