Cyclic nucleotide levels, protein phosphotransferase activities, and cyclic nucleotide-binding proteins have been determined and partially characterized in the mouse lymphosarcoma P1798. This system is used as a model to understand the function of these activities in a rapidly proliferating cell. Adenosine 3':5'-monophosphate (cAMP) concentrations are 5-fold higher in the lymphosarcoma cells th...

various cultured cells by actinomycin D or chromomycin A3 (1 1, 12, 23). In all these cell types, the nucleolar shape seems to reflect a low rate of nucleolar RNA synthesis. Although the ultrastructural morphology of undifferen tiated and well-differentiated cells of lymphosarcomas (poorly and well-differentiated malignant lymphomas) is very similar to leukemic lymphocytes in various stages of ...

Purpose of the study . To effect copper nanoparticles on characteristics transplanted tumors rats, as well to assess dependence method administration nanoparticles. Materials and methods In experiments 163 white outbred male 160–200 g, size growth rate sarcoma 45 Pliss' lymphosarcoma were determined in dynamics when a suspension physiological saline was injected intratumorally or intraperitonea...