BACKGROUND To assess the preoperative nutritional status of patients with various disorders and to provide data for pre- and postoperative patient management plans, particularly in the elderly. There is no published information on age-matched and disease-matched preoperative nutritional/immunologic status for orthopedic patients, especially in the elderly, in Jeju. METHODS In total, 331 patie...

BACKGROUND Immune reconstitution (IR) after hematopoietic stem cell transplantation (HSCT) reduces transplantation-related complications such as infection and improves HSCT outcomes. METHODS We retrospectively analyzed IR of lymphocyte subpopulations in 38 pediatric patients for hematologic malignant diseases after allogeneic HSCT from April 2006 to July 2008. T-cell-, B-cell-, and natural ki...

A study was done to investigate possible late central nervous system (CNS) complications of latent measles infection in hamsters. Signs of CNS disease, consisting of myoclonus and paralysis, occurred in some weanling hamsters inoculated intraperitoneally at 3 or 9 days of age with antithymocyte serum (ATS) and measles virus, but no late complications in adult life attributable to measles virus ...

Specific binding of aggregated gamma-globulin to a subpopulation of lymphocytes was demonstrated. This subpopulation was identified as the Ig-staining or B lymphocytes. The binding was irreversible and independent of complement, pH, temperature, protein content of the medium, and divalent cations. Aggregates of large size were needed for optimal visualization. Evidence was obtained that the sit...

OBJECTIVES We describe our experiences with, and compare the outcomes of, 2 groups of renal transplant patients treated with thymoglobulin or antithymocyte globulin-Fresenius as induction therapy at transplant to reduce the incidence of acute rejection and prevent delayed allograft function. MATERIALS AND METHODS Twenty-four recipients of deceased-donor or living-donor kidney transplants rece...

AIM The present study was aimed to investigate the immunological competence of chlorpyrifos (CPF) insecticide after oral administration in layer chickens. MATERIALS AND METHODS A total of 20 White Leghorn birds were given CPF in drinking water at 0.3 ppm/bird/day (no observable effect level dose) for a period of 3-month. Immune competence status of layer birds and chicks hatched from CPF-trea...

The upstream activation site (UAS) of the yeast phosphoglycerate kinase gene (PGK) has been localised by deletion analysis (1). Here we show that the UASPGK contains two functionally distinct domains. These two domains, designated activator (A) and modulator (M), appear to be located within bases -460 to -402 and -531 to -461, respectively, relative to the initiating ATG; although it is possibl...

The International Symposium on Auto­ phagy (ISA) is an important meeting with a long history devoted solely to the topic of autophagy. Yoshimori Ohsumi (Tokyo Institute of Technology, Japan), who identified a series of autophagy­related genes (ATG genes) in yeast [1], proposed and organized the first ISA in Okazaki, Japan, in 1997. Over the years, the ISA sym­ posia have witnessed the explosive...

Large doses of antihuman lymphoblast globulin (AHLG) were used prophylactically in three recipients of renal allografts from living related donors. These recipients received 1, 500 mg/day of AHLG for 14 days begining on the second day before transplantation in addition to the standard immunosuppression. Serum AHLG levels, serum anti-AHLG antibodies and T cell subsets were checked serially. The ...