OBJECTIVES The aim of this study was to evaluate the relationship between left ventricular (LV) ejection fraction and clinical outcome to cardiac resynchronization therapy (CRT) in mild heart failure patients enrolled in MADIT-CRT [corrected]. BACKGROUND Left ventricular ejection fraction (LVEF) is a surrogate marker of heart failure (HF) status and associated risk. Data on the effectiveness ...

Backround: “Ablate-and-pace” is an established procedure for selected patients with drug-refractory atrial fibrillation (AF). As consecutive right-ventricular pacing might have deleterious effects on left ventricular ejection fraction (LVEF), cardiac resynchronisation therapy (CRT) has been proposed as an alternative. Our aim was to evaluate the long-term follow-up of LVEF of such patients, to ...

For the non-cardiologist emergency physician and intensivist, performing an accurate estimation of left ventricular ejection fraction (LVEF) is essential for the management of critically ill patients, such as patients presenting with shock, severe respiratory distress or chest pain. Our objective was to develop a semi-quantitative method to improve visual LVEF evaluation. A group of 12 sets of ...

BACKGROUND In asymptomatic patients with severe aortic stenosis, guidelines recommend left ventricular ejection fraction (LVEF) of <50% as the threshold for referral for aortic valve replacement. We investigated the importance of LVEF on long-term outcome after aortic valve replacement in symptomatic and asymptomatic patients with severe aortic stenosis. METHODS AND RESULTS We retrospectively...

BACKGROUND Preventive implantation of an implantable cardioverter defibrillator (ICD) early after myocardial infarction failed to demonstrate a survival benefit in patients with depressed left ventricular ejection fraction (LVEF). This may be explained by early recovery of the LVEF after percutaneous coronary intervention (PCI). We sought to determine the incidence of a sustained LVEF ≤35% in p...

BACKGROUND There is a known association between a depressed left ventricular ejection fraction (LVEF < 0.35) and increased mortality in patients undergoing coronary artery bypass graft (CABG) operations. Recent studies show that elevated preoperative LV end-diastolic pressure (LVEDP) is an independent predictor of operative death for patients undergoing CABG. Therefore, the purpose of this stud...

BACKGROUND To evaluate the relevance of stress-induced decrease in left ventricular ejection fraction (LVEF) in patients with type-2 diabetes. METHODS A total of 684 diabetic patients with available rest and post-stress gated myocardial perfusion single-photon emission computed tomography (MPS) data were enrolled. An automated algorithm was used to determine the perfusion scores using a 17-se...

BACKGROUND Left ventricular remodeling, as commonly measured by left ventricular ejection fraction (LVEF), is associated with clinical outcomes. Although change in LVEF over time should reflect response to therapy and clinical course, serial measurement of LVEF is inconsistently performed in observational settings, and the incremental prognostic value of change in LVEF has not been well charact...

BACKGROUND In patients with acute coronary syndrome (ACS), reduced left ventricular ejection fraction (LVEF) is a known marker for increased mortality. However, the relationship between LVEF measured during index ACS hospitalization and mortality and heart failure (HF) within 1 year are less well-defined. METHODS We performed a retrospective analysis of 445 participants in the IMMEDIATE Trial...