background: radiation-induced lung toxicity is an important dose-limiting toxicity in lung cancer radiotherapy, for which there are no generally accepted predictive factors. this study seeks to identify risk factors associated with the development of severe radiation-induced lung toxicity using clinical and dosimetric parameters. methods: we reviewed the medical records of 54 patients with hist...

Introduction: One of the treatment choices in breast cancer is Intra operative electron beam radiation therapy (IOERT). Due to high dose delivery in this procedure, shielding disk is used to protect organs at risk (OARs). In this study, we evaluate the OARs dose in the breast IOERT using Monte Carlo simulation with and without shielding disk in RANDO phantom. Material and Methods: Simulation ...

background: to investigate the expression of tnf-α, il-6, il-10 in the plasma of patients with lung cancer who received radiation therapy (rt), and to analyze the correlation between these cytokines and radiation pneumonitis (rp). materials and methods: patients with lung cancer who received 3d-crt in our hospital were prospectively evaluated. circulating cytokine levels were measured with elis...

Introduction: This study aims to compare the dose delivery parameters and radiobiologic model prediction of Tumor Control Probability (TCP) of the FIMRT technique compared with rectangular two tangential wedged fields (2FW) in the treatment of breast cancer. Furthermore, reduction of the heart and lung dose in the FIMRT was studied via dosimetric parameters and radiobiologic mo...

background: tangential irradiation of intact breast is one of the most common procedures performed in any radiotherapy center. this method is performed by using 2d and 3d treatment planning. the aim of this study was to compare 2d with 3d plans in breast conserving radiotherapy. homogeneity of isodose, and lung received dose were compared. materials and methods: twenty patients with breast canc...

Introduction:   The aim of this study is to investigate the effect of respiratory motion during radiation therapy in patient with lung cancer and comparison of dosimetric parameters between Intensity modulation radiation therapy and three-dimensional conformal radiotherapy in lung cancer.   Materials and Methods:   Two CT scan was performred for each pati...

Background: Tangential irradiation of intact breast is one of the most common procedures performed in any radiotherapy center. This method is performed by using 2D and 3D treatment planning. The aim of this study was to compare 2D with 3D plans in breast conserving radiotherapy. Homogeneity of isodose, and lung received dose were compared. Materials and Methods: Twenty patients with br...

Background: To investigate the expression of TNF-α, IL-6, IL-10 in the plasma of patients with lung cancer who received radiation therapy (RT), and to analyze the correlation between these cytokines and radiation pneumonitis (RP). Materials and Methods: Patients with lung cancer who received 3D-CRT in our hospital were prospectively evaluated. Circulating cytokine levels were measured wit...

Introduction: The functionality and quality of any treatment planning system (TPS) strongly depends on the type of Algorithm which is used by it. Obviously, the role of dose distribution algorithms in calculation of prescribed dose inside the tumor in modern radiotherapy techniques has more important than past to achieve the best clinical outcomes, especially in tumors which ar...