Calprotectin (CLP) is a heterodimer formed by two S-100 calcium-binding cytosolic proteins, S100A8 and S100A9. It multifunctional protein expressed mainly neutrophils released extracellularly activated or damaged cells mediating broad range of physiological pathological responses. has been more than 20 years since the implication S100A8/A9 in inflammatory process was shown; however, evaluation ...