AIM To study the dose-response of stage I non-small-cell lung cancer (NSCLC) in terms of long-term local tumor control (LC) after conventional and hypofractionated photon radiotherapy, modeled with the linear-quadratic (LQ) and linear-quadratic-linear (LQ-L) approaches and to estimate the clinical α/β ratio within the LQ frame. MATERIAL AND METHODS We identified studies of curative radiothera...

Liquiritigenin (LQ), an active component of licorice, has an inhibitory effect on LPS-induced inhibitory nitric oxide synthase expression. This study investigated the effects of LQ on choleresis, the expression of hepatic transporters and phase-II enzymes, and fulminant hepatitis. The choleretic effect and the pharmacokinetics of LQ and its glucuronides were monitored in rats. After intravenous...

The Gentzen-Kripke construction of the semantics for intermediate logic LQ, which is obtainable from the intuitionistic propositional logic H by adding the weak law of excluded middle -*A v —• —1>4, is presented. Our construction spans the Gentzen system and the Kripke semantics for LQ by providing the way from the cut-elimination theorem to model-theoretic results. The completeness and decidab...

and Applied Analysis 3 for any fixed T > 0. Then v,H can be extended beyond T > 0 if one of the following conditions is satisfied: 1 u ∈ C ( 0, T ;Ln/3 ) , 1.11 2 u ∈ L 0, T ;L with 2 p n q 3, n 3 < q ≤ n, 1.12 3 ∇u ∈ C ( 0, T ;Ln/4 ) , 1.13 4 ∇u ∈ L 0, T ;L with 2 p n q 4 with n 4 < q ≤ n 2 . 1.14 Remark 1.5. If we delete the harmless lower order terms ∂tu − Δu and ∂tB − ΔB in 1.1 and 1.2 , th...

The bilinear maximal operator defined below maps Lp × Lq into Lr provided 1 < p, q < ∞, 1/p + 1/q = 1/r and 2/3 < r ≤ 1. Mfg(x) = sup t>0 1 2t ∫ t −t |f(x+ y)g(x− y)| dy. In particular Mfg is integrable if f and g are square integrable, answering a conjecture posed by Alberto Calderón. 1. Principal results In 1964 Alberto Calderón defined a family of maximal operators by Mfg(x) = sup t>0 1 2t ∫...

Consider the standard linear regression model Y = Xβ+w, where Y ∈ R is an observation vector, X ∈ R is a design matrix, β ∈ R is the unknown regression vector, and w ∼ N (0, σI) is additive Gaussian noise. This paper studies the minimax rates of convergence for estimation of β for lp-losses and in the l2-prediction loss, assuming that β belongs to an lq-ball Bq(Rq) for some q ∈ [0, 1]. We show ...

$EVWUDFW 7KH DLP RI WKLV SDSHU LV WR H[SORUH WKH ZD\ LQ ZKLFK GLIIHUHQW NLQG RI OLQJXLVWLF YDULDEOHV FDQ EH XVHG LQ RUGHU WR GLVFULPLQDWH WH[W W\SH LQ SUHFODVVLILHG SUHVV WH[WV 0RGHUQ *UHHN 0* ODQJXDJH GXH WR LWV SDVW GLJORVVLF VWDWXV H[KLELWV H[WHQGHG YDULDWLRQ LQ ZULWWHQ WH[WV DFURVV DOO OLQJXLVWLF OHYHOV DQG FDQ EH H[SORLWHG LQ WH[W FDWHJRUL]DWLRQ WDVNV 7KH UHVHDUFK SUHVHQWHG XVHG 'LVFULPLQD...

Liquiritigenin (LQ), separated from Glycyrrhiza radix, possesses anti-inflammatory, antihyperlipidemic, and antiallergic effects. Our present study aims to investigate the antihepatocellular carcinoma effects of LQ both in cell and animal models. LQ strikingly reduced cell viability, enhanced apoptotic rate, induced lactate dehydrogenase over-release, and increased intracellular reactive oxygen...

In this article, we study the high resolution quantization problem for Rdvalued stochastic processes X that are solutions of stochastic differential equations. We let C([0, 1],Rd) denote the set of continuous functions mapping [0, 1] to Rd and denote by ‖·‖[0,1] the corresponding supremum norm, i.e. ‖f‖[0,1] = supt∈[0,1] |f(t)|. Analogously, Lq([0, 1],Rd) denotes the Lq-space of functions mappi...

A model of irradiated cell survival probability based on cell-cycle regulation of an avascular tumor is developed. It is shown, that for high doses as used in hypofractionated regimens the conventional linear quadratic (LQ) model grossly underestimate cell survival. The surviving fraction of tumor cells in hypoxic and normoxic conditions is calculated as a function of dose for an equivalent tum...