OBJECTIVE To evaluate the prognostic value of arrhythmogenic markers in hypertensive patients. DESIGN Two hundred and fourteen hypertensive patients without symptomatic coronary disease, systolic dysfunction, electrolyte disturbances or anti-arrhythmic therapy were included. Recordings were made of 12-lead standard ECGs with calculations of QT interval dispersion, 24 h Holter ECGs (204 patien...

The survey gives an overview of the achievements in topology of real algebraic varieties in the direction initiated in the early 70th by V. I. Arnold and V. A. Rokhlin. We make an attempt to systematize the principal results in the subject. After an exposition of general tools and results, special attention is paid to surfaces and curves on surfaces.

This is an introductory exposition to background material useful to appreciate various formulations of the Mordell–Lang conjecture (now established by recent spectacular work due to Vojta, Faltings, Hrushovski, Buium, Voloch, and others). It gives an exposition of some of the elementary and standard constructions of algebro-geometric models (rather than model-theoretic ones) with applications (...

ment of ventricular fibrillation at the time of cardiac operations, and has proved successful at other times (McDonald et al., 1963). Lown et al. (1962b) have described the use of directcurrent shock both experimentally and in the treatment of patients with atrial and ventricular arrhythmias (Lown et al., 1962a). The use of direct current enables the shock to be applied at a precise moment in t...

Intracardiac electrophysiological studies were performed in two patients with a documented history of repetitive supraventricular tachyarrhythmias. Case 1, with short PR interval and narrow QRS complexes had a short AH interval and intermittent right bundle-branch block. Thus the short PR wide QRS syndrome is not always a result of the Wolff-Parkinson-White syndrome but can also be seen in the ...

This challenge of medical overuse has been recognized by the Lown Institute in Brookline, Massachusetts, as well as by educators at the Cambridge Health Alliance in Cambridge, Massachusetts, and has given rise to a new educational conference format called ‘‘Right Care Rounds.’’ This conference uses the familiar format of a case presentation to explore and identify drivers of medical overuse and...

The association between the extent of left ventricular (LV) hypertrophy and severity of ventricular or atrial arrhythmias are examined. Two-dimensional echocardiography and 24-h Holter electrocardiography monitoring were performed in 60 patients with hypertrophic cardiomyopathy (HCM). According to the distribution of the LV hypertrophy, the patients were divided into three groups: 1. Apical hyp...

Synchronized direct current shock (Lown, Amarasingham, and Neuman, 1962) has rapidly become established as an effective and safe method of treating cardiac arrhythmias, but controversy remains about the use of antiarrhythmic drugs in maintaining sinus rhythm following the procedure. Although quinidine is potentially dangerous (Thomson, 1956; Oram and Davies, 1964; Davies, Leak, and Oram, 1965),...

The Covid-19 pandemic has forced many people to reconsider what medicine is all about. But debate over doctoring — and it not nothing new, 2021 marks significant anniversaries of the births two physicians who took a broad view medicine.