OBJECTIVE To compare phenotypes of 2 age-related macular degeneration (AMD) susceptibility genes: LOC387715 and complement factor H (CFH). METHODS Phenotypes of 755 AMD cases were characterized. The number of LOC387715 (T allele at rs10490924, or A69S) and CFH (T1277C at rs1061170, or Y402H) risk alleles were determined in each case. Individuals were divided into 5 groups by genotype: group 1...

IMPORTANCE A history of loss of consciousness (LOC) is frequently a driving factor for computed tomography use in the emergency department evaluation of children with blunt head trauma. Computed tomography carries a nonnegligible risk for lethal radiation-induced malignancy. The Pediatric Emergency Care Applied Research Network (PECARN) derived 2 age-specific prediction rules with 6 variables f...

Scene recognition is a core function of the visual system, drawing both on scenes' intrinsic global features, prominently their spatial properties, and on the identities of the objects scenes contain. Neuroimaging and neuropsychological studies have associated spatial property-based scene categorization with parahippocampal cortex, while processing of scene-relevant object information is associ...

BACKGROUND Consensus on whether physical condition affects the risk of gravity-induced loss of consciousness (G-LOC) has not been reached, and most previous studies about the issue did not include well-experienced aviators. We compared the physical conditions of well-experienced young aviators according to the occurrence of G-LOC during human centrifuge training. METHODS Among 361 young male ...

Granulomatosis with polyangiitis (GPA) is a life-threatening disease characterized by granulomatous inflammation and antineutrophil cytoplasmic antibody (ANCA) associated systemic vasculitis, classically involving upper and lower respiratory tracts and kidney. Milder forms of disease restricted to respiratory tract is referred to as localized GPA (loc-GPA) [1,2]. The European Vasculitis Study G...

OBJECTIVE The current study sought to examine executive function (EF) in overweight individuals with and without loss-of-control (LOC) eating. METHOD Eighty overweight and obese individuals entering a behavioural weight loss trial with (n=18) and without (n=62) LOC eating were administered a clinical interview and neuropsychological battery designed to assess self-regulatory control, planning...

locus of control is said to affect learners' academic achievement. this effect has scarcely been examined within general english context. this study is concerned with examining the differences in general english (ge) course achievement among university students of humanities, sciences, and engineering. it also explores the effect of locus of control (loc) in ge course achievement among these th...