Quantum dots are new types of fluorescent materials for biological labeling. As a result, QDs toxicity study is an essential requirement for future clinical applications. Therefore, the cytotoxic CdSe:ZnS quantum dots effects on some organs in mice are presented in this study. In this work, 10, 20 and 40 mg/kg doses of CdSe:ZnS quantum dots were injected to 32 adult male mice. Structural and op...

conclusions in conclusion, at measurement can be beneficial for the safety or recovery of malathion-induced toxic injury in liver tissue and liver mitochondria. results in liver tissue, the activity of lpo and cat was higher in the malathion group in comparison to controls. at reduced malathion-induced lpo, sod, cat, and gpx in rat liver. coadministration of at with malathion improved lpo, sod,...

background: garcinia kola seed is consumed indiscriminately in nigeria without recourse to its potential toxicity. therefore, this study was aimed at assessing the toxicity of the aqueous extract of g. kola seeds on selected tissues of male rats.  methods: thirty male rats (215.00 ± 18.58 g) were assigned into four groups: a, b, c and d which received 0.5 ml of distilled water, 25, 50 and 100 m...

Drug-induced liver toxicity is one of the leading causes of acute liver failure in the United States, exceeding all other causes combined. The objective of this paper is to describe systems biology methods for identifying pathways involved in liver toxicity induced by free fatty acids (FFA) and tumor necrosis factor (TNF)-alpha in human hepatoblastoma cells (HepG2/C3A). Systems biology approach...

conclusions hepatotoxicity of halogenated inhalational anesthetics has been well documented in available literature. halothane-induced liver injury was extensively acknowledged; however, the next generation halogenated anesthetics have different molecular structures and associated with less hepatotoxicity. although anesthesia-induced hepatitis is not a common occurrence, we must consider the as...

the study monitored the toxicity of environmentally relevant concentration of pesticides and metals in zebra fish danio rerio. zebra fish were exposed to environmentally relevant concentration of pesticides and metals for a period of 14 days. the individual and the combined toxicity of pesticides and metals were evaluated. the pesticides and metals treated groups showed histopathological altera...

objective(s): to appraise the antihepatotoxic efficacy of ethanolic extract of operculum turpethum root on the liver of swiss albino mice.   materials and methods:   hepatic fibrosis was induced in adult male albino mice through intraperitoneal administrations of n-nitrosodimethylamine (ndma) at the concentration of 10 mg/kg body weight. the liver toxicity and therapeutic effect of the plant et...

OBJECTIVE To investigate clinical and laboratory toxicity in patients with unresectable liver metastases, treated with yttrium-90 radioembolization ((90)Y-RE). METHODS Patients with liver metastases treated with (90)Y-RE, between February 1(st) 2009 and March 31(st) 2012, were included in this study. Clinical toxicity assessment was based on the reporting in patient's charts. Laboratory inves...

Background: Garcinia kola seed is consumed indiscriminately in Nigeria without recourse to its potential toxicity. Therefore, this study was aimed at assessing the toxicity of the aqueous extract of G. kola seeds on selected tissues of male rats.  Methods: Thirty male rats (215.00 ± 18.58 g) were assigned into four groups: A, B, C and D which received 0.5 ml of distilled water, 2...