Macromolecular proton fraction (MPF) and T1rho maps for two representative patients with F0 F2 stage fibrosis as confirmed by liver histology. (A) MPF from a patient fibrosis, (B) (C) the same (D) fibrosis. Jian Hou et al. (485–492).

The present investigation has been conducted to understand the hazardous effect of sublethal concentration of cadmium chloride solution (0.8ppm on the histology of the liver of the fish Channa striatus for a period of 45 days. The histopathological changes induced in the liver were cytoplasmic vacuolization of the hepatocytes, blood vessel congestion, inflammatory leucocytic infiltration and ne...

Latest data suggest that placental growth factor (PLGF), growth differentiation factor-15 (GDF-15) and hepatic growth factor (HGF) are involved in hepatic fibrogenesis. Diagnostic performance of these markers for non-invasive liver fibrosis prediction was evaluated based on liver histology and stiffness. In total 834 patients were recruited. Receiver-operating-characteristics were used to defin...

Histology is the diagnosis gold standard. Conventional biopsy presents artifacts, delays, or human bias. Digital histology includes automation and improved diagnosis. It digitalizes microscopic images of histological samples analyzes similar parameters. The present approach proposes novel use phase contrast in clinical digital to improve label-free fresh tissue slices prevents processing artifa...

Fish have habitats that are easily exposed to contamination from the environment such as heavy metal waste which can cause changes in structure and function of body tissues. One type enters river Lebong Regency River is gold mining processing uses mercury cyanide. Heavy metals enter organisms accumulation biomagnification occur bodies aquatic biota fish. There has been no research related fish ...

BACKGROUND The long term outcome of drug related liver disease is unknown. AIMS To study the natural history of histologically proved drug induced hepatotoxicity. METHODS 110 patients with liver biopsies coded either as drug induced liver disease or hepatitis/cholestasis of unknown aetiology were identified from hospital records 1978-1996. Review of case notes and histology identified 44 pa...

Background: This study evaluated the effects of the maternal immune system stimulation or suppression during the pregnancy on the development of the neonate’s immune system.Methods: A total of 20 female rats were divided into four groups. The groups were treated using Leishmania major, Salmonella typhimurium, Tacrolimus, and sterilized normal saline. The animals were mated after 3-time tr...

PURPOSE To noninvasively assess liver fibrosis using combined-contrast-enhanced (CCE) magnetic resonance imaging (MRI) and texture analysis. MATERIALS AND METHODS In this IRB-approved, HIPAA-compliant prospective study, 46 adults with newly diagnosed HCV infection and recent liver biopsy underwent CCE liver MRI following intravenous administration of superparamagnetic iron oxides (ferumoxides...