objective: cancer represents the second cause of mortality in the world. saffron as a medicinal plant is known for its anti-cancer and anti-depressant properties. in this randomized double blind clinical trial, the effects of saffron on response to treatment in patients suffering from liver metastasis were evaluated. materials and methods: thirteen patients suffering from liver metastases who r...

a new series of 1,2-diaryl-4,5,6,7-tetrahydro-1h-benzo[d]imidazoles, possessing trimethoxy phenyl pharmacophore, were synthesized to evaluate their biological activities as tubulin inhibitors. cytotoxic activity of the synthesized compounds 7a-f was assessed against several human cancer cell lines, including mcf-7 (breast cancer cell), hepg2 (liver hepatocellular cells), a549 (adenocarcinomic h...

Presented clinical case is a rare of poorly differentiated squamous cell non-keratinizing cancer the right lung with ingrowth into diaphragm and liver, metastatic liver damage in combination recurrent echinococcosis liver. Taking account epidemiological history, surgery, features radiation imaging results serology preoperative period, diagnosis “echinococcosis spread to lungs” was made, which t...

background: cell-based treatments are currently being actively received great attention among scientists and clinicians for a variety of diseases as well as diabetes .the aim of this study was to investigate the effect of allotransplantation of fetal liver-derived cell suspension in patients with type 1 diabetes. methods: patients with type 1 diabetes (n=16) aged 6-30 years-old were included in...

background: lung cancer is the most common cause of cancer death worldwide with an annual mortality rate of more than 1.3 million worldwide. we aimed to analyze the clinicopathological features of patients with non-small-cell lung cancer (nsclc) in west of iran. methods: 64 patients with nsclc who referred to our clinic were analyzed. sex, age, histopathology, location of the tumor, treatment, ...

: The most common sites for metastasis of lung cancer are the bones, liver, adrenal glands, and brain. Only a few studies have reported on perianal or perirectal cancer. Herein, we report case 78-year-old man who developed distant small cell carcinoma (SCLC), presenting as palpable mass pain in buttock, diagnosed through magnetic resonance imaging. Immunohistochemical staining confirmed from SC...

marine streptomyces are prolific producers of majority of bioactive secondary metabolites which are used in pharmaceutical industry as effective drugs against life threatening diseases. the cytotoxic activity of the pure compound 1, 2- benzene dicarboxylic acid, mono 2- ethylhexyl ester (dmehe) from marine derived actinomycete streptomyces sp. vitsjk8 was investigated against mouse embryonic fi...

amorphophallus campanulatus (roxb.) blume belonging to the family of araceae, is a perennial herb commonly known as elephant foot yam. its tuber has been traditionally used for the treatment of liver diseases, abdominal tumors, piles. the aim of the present study was to evaluate the dose-dependent cytotoxic and apoptosis inducing effects of the sub fractions of amorphophallus campanulatus tuber...