and the Dutch Diabetes Foundation. Special thanks to the general practitioners and pharmacists in the Ommoord district for their contributions to the Rotterdam Study and to the general practitioners in the Erasmus Rucphen Family (ERF) region for their contributions to the ERF study. Erasmus University and the Departments of Epidemiology & Biostatistics and Clinical Genetics provided fi nancial ...

The objective of this study was to evaluate the therapeutic safety and efficacy of percutaneous radiofrequency ablation (RFA) with Internally Cooled Electrode for malignant hepatic tumors; which were in contact with blood vessels. A total of 297 patients with malignant hepatic tumors (358 nodules) who underwent RFA, by means of straight Internally Cooled Electrodes, were enrolled in this study....

To provide health services to its population of 1.2 billion, China has 200 000 health establishments including 62 000 public hospitals (Ministry of Health 1996). China has some 3 million hospital beds in operation, averaging 2.4 beds per thousand people. This is a higher per capita ratio than is found in other low-income regions of the world. Three-quarters of China’s total health spending goes...

The systemic pharmacological treatment of disease is limited by severe toxicity to normal organs/tissue. Therefore, various delivery vehicles have been designed to carry therapeutic drugs to their target tissues. We designed a novel vehicle formed by the interaction of biotins in a DNA (polymer) with avidins (crosslink), resulting in a porous particle. This self-assembled (HSAM) nanoparticle ve...