Pathobiont expansion, such as that of adherent-invasive Escherichia coli (AIEC), is an emerging factor associated with inflammatory bowel disease. The intestinal epithelial barrier is the first line of defense against these pathogens. Inflammation plays a critical role in altering the epithelial barrier and is a major factor involved in promoting the expansion and pathogenesis of AIEC. AIEC in ...

Membrane-anchored mucins are present in the apical surface glycocalyx of mucosal epithelial cells, each mucosal epithelium having at least two of the mucins. The mucins have been ascribed barrier functions, but direct comparisons of their functions within the same epithelium have not been done. In an epithelial cell line that expresses the membrane-anchored mucins, MUC1 and MUC16, the mucins we...

We deene the notion of self-concordance of order two for the restriction f of a logarithmic barrier function to a given line. Based on this notion we prove an inner approximation of the domain of f, as well as a lower bound of the distance from a point t to the minimum of f. These results provide the theoretical tools to develop a simple and eecient search step for nding the minimum of the barr...

The energy barrier for the cross slip of screw dislocations in face-centered cubic (FCC) nickel as a function of multiple stress components is predicted by both continuum line tension and discrete atomistic models. Contrary to Escaig's claim that the Schmid stress component has a negligible effect on the energy barrier, we find that the line tension model, when solved numerically, predicts comp...

In this paper, we consider a primal-dual interior point method for solving nonlinear semidefinite programming problems. By combining the primal barrier penalty function and the primal-dual barrier function, a new primal-dual merit function is proposed within the framework of the line search strategy. We show the global convergence property of our method.

background: psychological and behavioral domains are important in coping with type ii diabetes. this study was conducted to assess supportive and coping obstacles in living with type ii diabetes among patients who visited hospitals affiliated to tehran university of medical sciences (tums). methods: this was a cross-sectional study with 600 subjects who participated in the study. data collectio...

Infants follow the gaze direction of others from the middle of the first year of life. In attempting to determine how infants understand the looking behavior of adults, a number of recent studies have blocked the adult's line of sight in some way (e.g. with a blindfold or with a barrier). In contrast, in the current studies an adult looked behind a barrier which blocked the child's line of sigh...

Primary barrier determinations for the shielding of medical radiation therapy facilities are generally made assuming normal beam incidence on the barrier, since this is geometrically the most unfavorable condition for that shielding barrier whenever the occupation line is allowed to run along the barrier. However, when the occupation line (for example, the wall of an adjacent building) runs per...

Quantum tunneling between two potential wells in a magnetic field can be strongly increased when the potential barrier varies in the direction perpendicular to the line connecting the two wells and remains constant along this line. An oscillatory structure of the wave function is formed in the direction joining the wells. The resulting motion can be coherent like motion in a conventional narrow...

Two dimensional noise barrier studies investigate the insertion loss in the shadow zone of an infinite noise barrier for a coherent line source. Such models are often preferred to avoid the high computational cost of three dimensional models. The major limitation of two dimensional barrier models is the constant cross section of the barrier in the third direction. This paper presents a new solu...