BACKGROUND Kleine-Levin syndrome is a rare sleep disorder of unknown etiology. It is characterized by intermittent periods of excessive sleepiness, cognitive disturbances and behavioral abnormalities. Nine cases of familial Kleine-Levin syndrome have been identified, but there are no reported cases describing twins that are affected by the syndrome. CASE PRESENTATION We report the cases of 16...

Jarcho-Levin syndrome (JLS) is a rare congenital disorder characterized by the presence of vertebral and rib malformations at birth, first described in 1938 by Jarcho and Levin [1,2]. The majority of reported cases have originated in Puerto Rico, it seems that this syndrome is more common in patients with Spanish ancestors. Its frequency in Spain is 0.2 per 100000 newborns with a female predomi...

BACKGROUND Jarcho-Levin syndrome, also known as spondylothoracic dysplasia and spondylocostal dysplasia, is characterized by varieties of vertebrae and rib anomalies. Jarcho-Levin syndrome is a clinical-radiological diagnosis with clinical evidence of short neck, short trunk, normal-sized limbs, or increased arm span, and vertebral and rib defects on the skeletal survey. CASE REPORT About 400 c...

Two cases of Kleine-Levin Syndrome with illness duration of three and four months respectively are presented. Both cases in their adolescence presented with typical features of the syndrome-onset after high grade fever episodic course and spontaneous remission of each episode and normalcy in between the episodes Characteristic features of each episode in both cases were hypersomnia, eating exce...