The aim of this study is to prepare fluvastatin nanostructured lipid carriers (FLV-NLCs) in order to find an innovative way to alleviate FLV-associated disadvantages. The limitations include poor solubility and extensive first-pass metabolism, resulting in low (30%) bioavailability and short elimination half-life (1-3 hours). FLV-NLCs were prepared by hot emulsification-ultrasonication method. ...

An investigator who plans to conduct an experiment with multiple independent variables must decide whether to use a complete or reduced factorial design. This article advocates a resource management perspective on making this decision, in which the investigator seeks a strategic balance between service to scientific objectives and economy. Considerations in making design decisions include wheth...

A new class of two-level non-regular fractional factorial designs is defined. We call this class an affinely full-dimensional factorial design, meaning that design points in the design of this class are not contained in any affine hyperplane in the vector space over F2. The property of the indicator function for this class is also clarified. A fractional factorial design in this class has a des...

1. In poultry investigations, the main interest is often to study the effects of many factors simultaneously. Two or three level factorial designs are the most commonly used for this type of investigation. However, it is often too costly to perform when number of factors increase. So a fractional factorial design, which is a subset or a fraction of a full factorial design, is an alternative. Th...

We give a combinatorial interpretation for the super Catalan number S(m,m + s) for s ≤ 3 using lattice paths and make an attempt at a combinatorial interpretation for s = 4. We also examine the integrality of some factorial ratios.

The effect of the Transcendental Meditation (TM) technique on working memory and field independence was investigated in a twelve-week longitudinal time-series study in which the uMatch Me" computerized memory game and the Rod and Frame Test were administered daily to a matched pair of 11-year-old boys and a matched pair of 14-year-old girls. One of the boys and one of the girls began the TM tec...