PURPOSE To describe a case of a child with a known history of pigmentary mosaicism suggestive of Hypomelanosis of Ito presenting with unilateral leukocoria, who was ultimately diagnosed with retinoblastoma. METHODS A report of a 16-month-old girl with pigmentary mosaicism and unilateral retinoblastoma. RESULTS A previously healthy 16-month-old girl with a diagnosis of a mosaic hypopigmentat...

This is a retrospective investigation of patients with Retinoblastoma (RB) conducted from 2013 to 2016 at the Quanzhou Maternal and Child Health Hospital (China). Demographic and clinical characteristics, treatment outcomes, and risk factors were studied. In total, 436 patients were included in the study. Most of the findings obtained in this study are consistent with other previous reports. Th...

BACKGROUND Retinoblastoma is a malignant intraocular tumour of childhood, if not detected early, it results in loss of eye as well as life. The Objective was to study the pattern of presentation of Retinoblastoma in order to detect the disease at an earlier stage. It was conducted at Supra Regional Referral Centre for Retinoblastoma, Department of Ophthalmology, Khyber Teaching Hospital, Peshaw...

PURPOSE To report the outcome of intraocular lens (IOL) implantation in pediatric eyes with posterior lentiglobus. METHODS Retrospective chart review of pediatric cataract surgery cases with primary IOL implantation. RESULTS Of 553 eyes that received IOL implantation by the lead author, 364 eyes were identified as having been implanted with an IOL at the time of surgery for a nontraumatic c...

Coats disease is an idiopathic nonhereditary condition retinal vascular disorder characterized by telangiectasia with intraretinal and/ or subretinal exudation. Unilateral involvement in young males the typical presentation most cases being diagnosed first and second decade of life and, if untreated, can lead to total detachment secondary glaucoma, sometimes requiring enucleation. The common pr...

OBJECTIVE One of the primary factors in managing patients with retinoblastoma is early diagnosis. The main idea of this study was to recognize the consequences of delay in diagnosis on therapy of the disease. METHODS A retrospective review of all children with proven retinoblastoma, who had presented to MAHAK hospital in Tehran, from April 2007 to Dec 2011, was performed. Grouping of intraocu...

A clinical isolate of type I Herpes virus was injected intracerebrally in 4-week-old Balb/C mice. Bilateral ocular disease was observed initially clinically as a leukocoria and an anterior uveitis on the 7th to 11th postinjection days. By day 21 an organized vascularized retrolental membrane had formed with resolution of active inflammation and secondary cataract formation. Light microscopy rev...

tumor that shows spontaneous regression but often resembles welldifferentiatedsquamouscell carcinomahistopathologically.Likesquamous cellcarcinoma,keratoacanthomamay show cellular atypia, mitosis, horn pearls, and focally infiltrativegrowth. In the present case, the initial microscopicsectiondidnotshowakeratotic plug,andthe firstdiagnosiswassquamouscell carcinoma.However, additional sections cu...

Early and accurate detection of eye disorders in children can present a challenge for family physicians. Visual acuity screening, preferably performed before four years of age, is essential for diagnosing amblyopia. Cover testing may disclose small-angle or intermittent strabismus. Leukocoria, which is detected with an ophthalmoscope, may indicate retinoblastoma or cataract. Children with glauc...