Background: Insecticides may have negative effects on reproductive organs. Given the interaction between leptin and the hypothalamic-pituitary-gonadal (HPG) axis, we sought to investigate the changes in leptin and the HPG axis in adult male rats poisoned with Proteus and Biscaya insecticides. Methods: Our experimental subjects were 110 adult male Wistar rats (80–90 days of age; average weight=2...

conclusions changes in neonatal leptin levels can reflect changes in the body fat tissue and neonatal birth weight and could be effective in predicting weight gain in newborns with mothers who have gestational diabetes and may reduce birth trauma or future complications. results serum leptin levels in the cord blood of mothers with gdm were significantly higher than in normal mothers. there was...

Background Leptin, as a key hormone in energy homeostasis, plays an important role in reproduction and male fertility. However, its negative or positive effect on sperm quality and assisted reproduction technique is still controversial. The aim of this study was the comparison of seminal leptin concentration in selected couples with male and female factor for intracytoplasmic microinjection (IC...

background: polycystic ovary syndrome (pcos) is the most common endocrinopathy in women. it may involve an impairment in physiologic regulation of leptin and ghrelin. there is limited, controversial data on the relation of dietary components with leptin and ghrelin in pcos, so the current study has been conducted to explore the effects of different macronutrients on serum levels of leptin and g...

objectives: leptin is a hormone-like protein produced by the adipose tissue. it plays an important role in protection of host against inflammation and infection. some studies have reported changes in leptin levels in the gingival crevicular fluid (gcf), saliva and blood serum of patients with periodontal disease compared to healthy individuals. the aim of the present study was to compare the sa...

The hormone leptin is released by adipocytes accordingly to current energy stores suppress appetite. Apart from this, acts as a proinflammatory cytokine and strongly stimulates inflammation. Immune-modulating properties are partly achieved affecting T-cell maturation, polarization, viability. Leptin rises inflammatory cells count, increases secretion, impairs regulatory T-lymphocytes differenti...

Background Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women. It may involve an impairment in physiologic regulation of leptin and ghrelin. There is limited, controversial data on the relation of dietary components with leptin and ghrelin in PCOS, so the current study has been conducted to explore the effects of different macronutrients on serum levels of leptin and gh...

objective(s): leptin is a hormone secreted by adipose tissue and is involved not only in the regulation of feeding and energy expenditure, but also its role in memory enhancement has been demonstrated as well. the partial transfer of leptin across the blood-brain barrier in obese individuals causes leptin resistance and prevents leptin reaching brain. on the other hand, studies have shown that ...