BACKGROUND Several epidemiological investigations show a correlation between cataract development and the dose of ultraviolet radiation (UVR) received. It is experimentally well established that exposure of animal eyes to UVR induces cataract. Most cataracts develop as a gradual increase in lens opacity. Despite this, current estimations of toxicity for cataract are based on the concept that ca...

Elevated cataract risk after radiation exposure was established soon after the discovery of X-rays in 1895. Today, increased cataract incidence among medical imaging practitioners and after nuclear incidents has highlighted how little is still understood about the biological responses of the lens to low-dose ionizing radiation (IR). Here, we show for the first time that in mice, lens epithelial...

results the electrophysiology laboratory staff received higher doses of ionizing radiation (17.2 ± 11.9 msv; p < 0.001). there was a significant positive correlation between the years of working experience and effective dose in the lens (p < 0.001). in general, our findings showed that the incidence of lens opacity was 79% (95% ci, 69.9-88.1) in participants with exposure (the case group) and o...

The present study reveals the pharmacological effect of chlorogenic acid, a major phenolic compound in plants, food, and coffee, on diabetic cataracts. Chlorogenic acid examined the inhibitory effects upon rat lens aldose reductase (AR) activity and xylose-induced rat lens opacity. The effect of chlorogenic acid on high glucose-induced cytotoxicity in lens epithelial cells was also examined. Ch...

The International Atomic Energy Agency (IAEA) safety requirements: 'General Safety Requirements Part 3--Radiation protection and safety of radiation sources: International Basic Safety Standards' (BSS) was approved by the IAEA Board of Governors at its meeting in September 2011, and was issued as General Safety Requirements Part 3 in July 2014. The equivalent dose limit for the lens of the eye ...

The equivalent dose limit for the eye lens for occupational exposure recommended by the ICRP has been reduced to 20 mSv y(-1) averaged over defined periods of 5 y, with no single year exceeding 50 mSv. The compliance with this new requirement could not be easy in some workplace such as interventional radiology and cardiology. The aim of this study is to evaluate different possible approaches in...

in view of the rapid expansion of contact lens amongst the users, new dimensions have been added to the domain of ophthalmology: giant papillay conjunctivitis, a disease caused by different kinds of contact lens, appears weeks or months after they are used, although some patients are struck years later. the predominant symptoms are increased awareness of lenses, ocular itching, blurred vision a...

PURPOSE To estimate ocular radiation doses and prevalence of lens opacities in a group of interventional catheterization professionals and offer practical recommendations based on these findings to avoid future lens damage. MATERIALS AND METHODS Subjects included 58 physicians and 69 nurses and technicians attending an interventional cardiology congress and appropriate unexposed age-matched c...

background: increased oxygen free radical and reduced glutathione level in the eye lens are important risk factor for cataract formation. the antioxidative property and increasing cellular and extra cellular glutathione level have been reported by several herbal medicines including silymarin.  objective: in present interventional study silybum marianum l. seed extract (silymarin) was tested aga...