Over the past two decades, a significant contribution to the pathophysiology of heart failure (HF) has been attributed to alterations of Ca2+ handling, which has been observed in myocytes isolated from failing hearts. Initially, a reduced Ca2+ transient amplitude due to a reduced Ca2+ reuptake rate by SERCA and enhanced extrusion of Ca2+ to the extracellular space by the Na+/Ca2+ exchanger had ...

Submit Manuscript | http://medcraveonline.com Abbreviations: LPP: Leak Point Pressure; DLPP: Detrusor Leak Point Pressure; ALPP: Abdominal Leak Point Pressure; SLPP: Stress Leak Point Pressure; VLPP: Valsalva Leak Point Pressure; CLPP: Cough Leak Point Pressure; SUI: Stress Urinary Incontinence; UDS: Urodynamic Study; ISD: Intrinsic Sphincter Dysfunction; IUS: Internal Urethral Sphincter, EUS: ...

landfill is the major method of solid waste disposal in developing countries. to protect soil andgroundwater from contamination, anti-seepage systems have to be installed in landfills. however, during theconstruction of anti-seepage system, many factors can result in holes in geomembrane liners. for the purpose of improving construction quality, the construction company needs to find the leaks ...

Deoxygenation-induced red blood cell (RBC) sickling probably activates multiple cation leak pathways. In an attempt to model this, we examined the net passive K efflux ("K leak") from normal and sickle RBCs undergoing elliptical deformation in hypotonic media (200 mOsmol/L). This hypotonic deformation activates two deformation-dependent K leak pathways that are not detectable during the balance...

We examine the use of model-checking in the analysis of information leakage in social networks. We take previous work on the formal analysis of digital crowds and show how a variation on the formalism can naturally model the interaction of people and groups of followers in intersecting social networks. We then show how probabilistic models of the forwarding and reposting behaviour of individual...

Research in psychology has shown that when people are told not to think about a pink elephant they cannot avoid doing just that. Similar results are found for language production in that people leak information about hidden figures when instructed to ignore those figures. It is argued that the salience of information plays a crucial role in these effects. The present study investigates how diff...

When it comes to granting mobile code access to conndential information , great care has to be taken if the code originates from an untrused source and the information is to remain conndential. If the program has access to the Internet during its execution, it has the possibility to leak information in many subtle ways, including through its temporal behaviour. This paper reports on practical e...

Introduction: Congenital anomalies of the cochlea and labyrinth can be associated with meningitis and varying degrees of hearing loss or deafness. Despite antibiotics, meningitis remains a life threatening complication.   Case Report: We report a case of recurrent meningitis following episodes of otitis media in a cochlear implantee child with bilateral vestibulocochlear malformation, due to f...

One of the numerous ways of addressing the Android malware threat is to run malicious applications in a sandbox environment while monitoring metrics. However, dynamic malware analysis is usually concerned with a one-time execution of an application, and information about behaviour in different environments is lacking in the literature. We fill this gap with a fuzzy-like approach to the problem:...