To determine if plasma lipoproteins interact and therefore possibly regulate intestinal lipoprotein metabolism, we investigated the binding, internalization, and degradation of 125I-labeled low density lipoprotein (LDL) and high density lipoprotein (HDL) by enzyme-dispersed rat intestinal mucosal cells. Both human and rat LDL and HDL were bound, internalized, and degraded in a concentration-dep...

High density lipoproteins (HDL) have been reported to inhibit oxidation of low density lipoproteins (LDL) based in part on observations that oxidative changes occur more slowly in LDL-HDL mixtures than in LDL alone. In the current studies, we developed an approach to discern particle-specific oxidation kinetics within mixed particle systems using the oxidation-labile fluorescent probe parinaric...

La variabilité intra-individuelle du cholestérol, et plus précisément LDL-cholestérol, mais, possiblement aussi, celle HDL-cholestérol apparaissent comme potentiellement délétères. Plusieurs études ont objectivé une association indépendante entre la d’une part, le risque d’accidents cardiovasculaires (infarctus myocarde, accident vasculaire cérébral) mortalité globale, d’autre part. Par ailleur...

Particle size of low density (LDL) and high density (HDL) lipoproteins and cholesterol esterification rate in HDL plasma (FER(HDL)) are important independent predictors of coronary artery diseases (CAD). In this study we assessed the interrelations between these indicators and routinely examined plasma lipid parameters and plasma glucose concentrations. In 141 men, healthy volunteers, we examin...

Background The significant association between total cholesterol (TC), non-high-density lipoprotein cholesterol (non-HDL), and low-density lipoprotein cholesterol (LDL) has been shown to be associated with Apolipoprotein B (Apo B). The objective of this study was to assess whether abnormal levels of TC, non-HDL and LDL can be used as predictors of abnormal serum Apo B levels. Results TC (r = ...

Regular physical activity with adequate intensity, according to WHO recommendations, can prevent various chronic diseases, such as heart disease, diabetes mellitus, cancer, and bone disease. Physical improve lipid profil: triglycerides, total cholesterol, HDL cholesterol (HDL-C), LDL (LDL-C). The aim of this study was compare profiles, which include levels (LDL-C) at different activity: low, me...

background & aim: policosanol is a component from main alcohol groups with long-chain that extracted from cane sugar. in the present research, the effect of policosanol was investigated on decrease of lipid metabolite levels in blood of hypercholesterolemia rats. experimental: a number of 32 male wistar rats race with average weight of 250 g was divided into four groups including negative ...

BACKGROUND We aimed to predict the abnormal LDL level by using TG, TC, HDL, and non-HDL in this study. MATERIAL AND METHODS Triglyceride (TG), total cholesterol (TC), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) data were obtained from the Laboratory Information System (LIS) for 4 years (Oct 1, 2013 to Sept 30, 2017) from among 34 270 healthy Chinese patients at Shuyang Peo...

Pulse-chase incubations of human plasma with [3H]cholesterol-laden skin fibroblasts or low density lipoproteins (LDL) and nondenaturing two-dimensional electrophoresis were used to study the transfer and esterification of cell-derived unesterified cholesterol (UC) in human plasma lipoproteins. Specific radioactivities ([3H]UC per microgram of UC) were calculated, and net cholesterol mass transf...