BACKGROUND Lycium barbarum polysaccharide (LBP) is a natural functional component that has a variety of biological activities. The molecular structures and apoptosis-inducing activities on human hepatoma SMMC-7721 cells of two LBP fractions, LBP-d and LBP-e, were investigated. RESULTS The results showed that LBP-d and LBP-e both consist of protein, uronic acid, and neutral sugars in different...

Liver is the main organ for lipopolysaccharide (LPS) clearance. Sensitization to LPS is associated with the upregulation of LPS-binding protein (LBP) in animal models. Therefore, we hypothesized that LBP could induce LPS sensitization through enhancing hepatic uptake of LPS. In this study, we examined the role of LBP in pathogenesis of LPS induced systemic inflammatory response syndrome (SIRS)....

introduction: approximately, 30-40% of general population experience at least one episode of low back pain (lbp) annually. research on lbp in adolescents is of great value, as it seems to be a major contributing factor for lbp in adulthood. this study was designed to assess lbp characteristics and its disability in mazandaran province secondary school children in 2004. materials and methods: th...

Introduction: It is widely accepted that musculoskeletal injuries, especially in the lumbar region, are among the most common complaints of people working in emergency medical services (EMS). This study aimed to determine the prevalence of low back pain (LBP) and its associated factors in the field staff of prehospital EMS in northern Iran. Methods: This cross-sectional descriptive correlation...

Purpose. To study the association of self-reported pain in adolescence with low back pain (LBP) in adulthood among mine workers and, also, study associations between the presence of LBP over 12-month or one-month LBP intensity during a health examination and daily ratings of LBP three and nine months later. Methods. Mixed design with data collected retrospectively, cross-sectionally, and prospe...

The aim of this study was to investigate the actual situation of low back pain (LBP) prevention in care workers with questionnaires, and this data were used to clarify and decrease LBP factors. Subjects were 52 care workers (30.7 ± 10.0 years old) in a nursing home who filled out two kinds of questionnaires about LBP, one about the prevalence of LBP (QN1) and the other about LBP control measure...

BACKGROUND Prevalence of low back pain (LBP) rises rapidly during adolescence, reaching adult levels by the age of 18. It has been suggested that adolescent LBP is benign with minimal impact, despite limited evidence. METHODS The aim of this study was to investigate the impact of LBP and the influence of chronicity, gender and presence of other spinal pain comorbidities at age 17. Subjects (n...

BACKGROUND Lipopolysaccharide binding protein (LBP) is an acute-phase protein produced by the liver. It has been shown that LBP plays an important role in the inflammatory response to sepsis. LBP has also been shown to protect animals from endotoxin challenge by facilitating the removal of endotoxin from the blood circulation. Cirrhotic patients are susceptible to bacterial infection. It is unk...

BACKGROUND Determining the association between body composition and low back pain (LBP) will improve our understanding of the mechanisms by which obesity affects LBP, and inform novel approaches to managing LBP. The aim of this study was to examine the relationship between body composition and LBP intensity and disability. METHODS A total of 5058 participants (44% men) of the Australian Diab...

Lipopolysaccharide binding protein (LBP) is an acute-phase reactant that binds bacterial LPS. We show that LBP binds to the surface of live Salmonella and to LPS coated erythrocytes (ELPS), and strongly enhances the attachment of these particles to macrophages. LBP bridges LPS-coated particles to macrophages (MO) by first binding to the LPS, then binding to MO. Pretreatment of ELPS with LBP ena...