نتایج جستجو برای: lamina mucosa aerosol

تعداد نتایج: 76987  

Journal: :Gut 2003
G Mazzarella M Maglio F Paparo G Nardone R Stefanile L Greco Y van de Wal Y Kooy F Koning S Auricchio R Troncone

BACKGROUND Studies on intestinal T cell clones from the mucosa of patients with coeliac disease have led to the identification of immunogenic gliadin epitopes. One is HLA-DQ8 restricted, its recognition by T cells being increased by introduction of negatively charged residues operated by tissue transglutaminase. AIM To test HLA-DQ8 restricted epitope in both native (QYPSGQGSFQPSQQNPQA) and de...

2002
G Mazzarella R Troncone

Background: Studies on intestinal T cell clones from the mucosa of patients with coeliac disease have led to the identification of immunogenic gliadin epitopes. One is HLA-DQ8 restricted, its recognition by T cells being increased by introduction of negatively charged residues operated by tissue transglutaminase. Aim: To test HLA-DQ8 restricted epitope in both native (QYPSGQGSFQPSQQNPQA) and de...

2014
Jutta Schröder-Braunstein Judith Gras Benedikt Brors Sonja Schwarz Timea Szikszai Felix Lasitschka Guido Wabnitz Antje Heidtmann Young-Seon Lee Serin Schiessling Christine Leowardi Mohammed Al-Saeedi Alexis Ulrich Antonia Engelke Johannes Winter Yvonne Samstag Thomas Giese Stefan Meuer

Resident human lamina propria immune cells serve as powerful effectors in host defense. Molecular events associated with the initiation of an intestinal inflammatory response in these cells are largely unknown. Here, we aimed to characterize phenotypic and functional changes induced in these cells at the onset of intestinal inflammation using a human intestinal organ culture model. In this mode...

Journal: :Gut 1998
P Anton J O'Connell D O'Connell L Whitaker G C O'Sullivan J K Collins F Shanahan

BACKGROUND The bacterial chemotactic peptide N-formyl-methionine-leucine-phenylalanine (FMLP) is produced by enteric flora and is one of the factors implicated in contributing to inflammatory bowel disease. Expression of receptors for FMLP on human phagocytes (polymorphs and monocytes) is well established, but there is conflicting evidence regarding the potential expression of FMLP receptors on...

Journal: :Journal of Translational Internal Medicine 2023

Abstract Background and Objectives Transcutaneous point-of-care ultrasound (POCUS) is a good tool to monitor the trachea in many clinical practices. The aim of our study verify feasibility POCUS-guided submucosal injection as potential drug delivery method for treatment tracheal stenosis. Materials methods inner wall was monitored via bronchoscope during methylene blue fresh ex vivo porcine eva...

Journal: :Gut 1983
G B Lindop

A case of megacolon is described in which there was an unusual and focal hyperplasia of enterochromaffin cells in the mucosa. These formed discrete spherical acini in the lamina propria. These acini were not neoplastic and their significance is discussed.

Journal: :American journal of rhinology 2006
Usama Mahmood James Ridgway Ryan Jackson Shuguang Guo Jianping Su William Armstrong Terry Shibuya Roger Crumley Zhongping Chen Brian Wong

BACKGROUND Optical coherence tomography (OCT) is an emerging imaging modality that uses light to produce in vivo high-resolution cross-sectional images (7 microm) of tissues to depths of up to 3 mm. OCT is analogous to ultrasound, but relies on interferometry and low-coherence optical sources to produce images of tissue structure at the histological level. METHODS In this study, OCT was used ...

Journal: :Folia morphologica 2002
Stanisław Moskalewski Dorota Biernacka-Wawrzonek Justyna Klimkiewicz Rafał Zdun

Blood from the glandular part of hamster gastric mucosa is drained by collecting venules, running from the subepithelial layer towards lamina muscularis mucosae. To visualise vessels involved in the venous outflow, hamsters were exposed to atropine and subjected to intravital ligation of portal vein, causing strong hyperaemia. Distribution of vessels and their connections were studied a) in tra...

Journal: :Folia histochemica et cytobiologica 2011
Bożena Kosztyła-Hojna Anna Andrzejewska Diana Moskal Joanna Kasperuk Dawid Falkowski Marek Rogowski

Vocal folds play a crucial role in voice production. The physiological vibrations of vocal folds depend on the unchanged multilayered structure of the vocal folds mucosa. Morphological changes of mucosa are the cause of voice quality disorders - dysphonia. The aim of this study was to determine the morphological base of dysphonia in patients with vocal folds atrophy. A group of 24 patients with...

Journal: :Gut 1998
H Kimura R Hokari S Miura T Shigematsu M Hirokawa Y Akiba I Kurose H Higuchi H Fujimori Y Tsuzuki H Serizawa H Ishii

BACKGROUND Increased production of reactive metabolites of oxygen and nitrogen has been implicated in chronic inflammation of the gut. The object of this study was to examine the magnitude and location of nitric oxide synthase (NOS) activity and peroxynitrite formation in the colonic mucosa of patients with ulcerative colitis in relation to the degree of inflammation. SUBJECTS Thirty three pa...

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