Numerous studies have been concerned with effects of orally administered antibiotics upon the numbers and kinds of microorganisms in the feces of man, but the influence of antibiotics upon intestinal lactobacilli, shown by changes in the numbers and kinds of these bacteria in feces, has not been thoroughly investigated. Enumeration and isolation of fecal lactobacilli have been facilitated by th...

Lactobacilli are probiotic commensal bacteria and potent modulators of immunity. When present in the gut or supplemented as probiotics, they beneficially modulate ex vivo immune responsiveness. Further, factors derived from several lactobacilli strains act immune regulatory in vitro. In contrast, Staphylococcus aureus (S. aureus) is known to induce excessive T cell activation. In this study, we...

background : the aim of this study was to compare the antimicrobial activity of watermelon juice probioticated using differ­ent strains of lactobacilli against salmonella typhi murium. methods : probioticated watermelon juice was produced using four strains of lactobacilli (lactobacillus casei, l. acidophil­lus, l. fementum and l. plantarum ). the watermelon juice was pasteurized for 30 minutes...

BACKGROUND The primary objective of this study was to investigate if supplementary lactobacilli treatment could improve the initial cure rate after vaginal clindamycin therapy, and secondly, if lactobacilli as repeated adjunct treatment during 3 menstrual cycles could lengthen the time to relapse after initial cure. METHODS Women (n = 100) with bacterial vaginosis diagnosed by Amsel criteria ...

BACKGROUND Anthrax is caused by the bacterium Bacillus anthracis and is regarded as one of the most prominent bioterrorism threats. Anthrax toxicity is induced by the tripartite toxin complex, composed of the receptor-binding anthrax protective antigen and the two enzymatic subunits, lethal factor and edema factor. Recombinant lactobacilli have previously been used to deliver antibody fragments...

The human vaginal microbiome is dominated by bacteria from the genus Lactobacillus, which create an acidic environment thought to protect women against sexually transmitted pathogens and opportunistic infections. Strikingly, lactobacilli dominance appears to be unique to humans; while the relative abundance of lactobacilli in the human vagina is typically >70%, in other mammals lactobacilli rar...

BACKGROUND The increasing interest in probiotic lactobacilli in health maintenance has raised the question of potential risks. One possible side effect could be an increased acidogenicity in dental plaque. The aim of this study was to investigate the effect of probiotic lactobacilli on plaque lactic acid (LA) production in vitro and in vivo. METHODS In the first part (A), suspensions of two l...

During the past few years several investigators have reported the isolation of lactobacilli or lactobacilli-like organisms from the rumen liquor of cattle and sheep. Gall and Huhtanen (1951) isolated several gram positive, nonsporeforming rods from rumen fluid which produced lactic acid from glucose, but they were not further identified. Some lactobacilli found by Rodwell (1953) in a sheep's ru...