In in vitro tests, natural coniferous resin from the Norway spruce (Picea abies) is strongly antifungal. In this observational study, we tested the clinical effectiveness of a lacquer composed of spruce resin for topical treatment of onychomycosis. Thirty-seven patients with clinical diagnosis of onychomycosis were enrolled into the study. All patients used topical resin lacquer treatment daily...

BACKGROUND Nail psoriasis occurs in up to 50% of patients affected by psoriasis, with a significant impact on quality of life that leads to a real clinical need for new therapeutic options. AIM To confirm whether the strengthening and hardening properties of the hydroxypropyl-chitosan (HPCH) nail lacquer could improve the structure of the nail plates on psoriatic nails. MATERIALS AND METHOD...

BACKGROUND The use of topical antifungal agents in the treatment of onychomycosis is of great value in clinical practice as there are different limitations regarding the use of systemic treatment. OBJECTIVE To evaluate the efficacy and safety of a nail lacquer formulation containing ciclopirox 8% in two different posologies: the traditional regimen (3/2/1) and a regimen of weekly use. METHO...

An autopsy case of suicide by ignition using lacquer thinner is presented. A wholly-charred body of a 54-year-old man and a can of lacquer thinner were found at the burnt driver's seat of a truck. Organic solvents in blood, urine, lung tissue, trachea and gastric contents and of the remaining clothes have been analyzed by gas chromatography/mass spectrometry (GC/MS). High levels of toluene, eth...

This study investigated the effect of board type (unmodified vs. MAPE modified) on the surface quality and thickness swelling-water absorption properties of recycled high density polyethylene (HDPE) based wood plastic composites. Additionally, two commercially available coatings (cellulosic coating and polyurethane lacquer coating) were also applied to composite surfaces and their adhesion stre...

The purpose of this randomized, clinical, double-blind short-term trial was to evaluate the efficacy of a new lacquer containing a new component (phosphonic acid methacrylate) designed for treating dentine hypersensitivity. Eighty-eight patients participated in this study. At the first visit one tooth was treated with the lacquer (1), while another tooth was treated with a placebo (2). Sensitiv...

INTRODUCTION Onychomycosis is the most common infectious disease involving nails. The aim of this study was to evaluate the antifungal activity of amorolfine 5% nail lacquer and three different acid-based medical devices indicated in the treatment of onychomycosis using an in vitro nail penetration assay. METHODS Four products were tested in vitro: (a) amorolfine 5% nail lacquer; (b) ethyl la...

AIMS To determine the incidence and predisposing findings for choroidal neovascularisation (CNV) in a large series of highly myopic patients. METHODS The medical records of 218 consecutive patients (325 eyes) with myopic fundus changes in the macula were reviewed. The incidence of CNV during a follow up of at least 3 years of highly myopic patients and identification of predisposing findings ...