Freely occurring alpha-l-aspartyl-l-histidine, beta-alanyl-l-histidine (carnosine), alpha-l-aspartyl-alpha-l-lysine, l-asparaginyl-alpha-l-lysine, alpha-l-glutamyl-alpha-l-lysine, l-isoleucyl-alpha-l-lysine, l-seryl-alpha-l-lysine, l-valyl-alpha-l-lysine and glycyl-alpha-l-lysyl-alpha-l-lysine were identified in young larvae (second and third instars) of the blowfly (Phormia regina).

The aim of the present study was to investigate the cataract preventive effect of dietary histidine regimes in adult Atlantic salmon (Salmo salar L.) in seawater, both through manipulating the dietary histidine level and feeding period. Mean body weight of individually tagged Atlantic salmon at the start of the experiment was 1662 (sd 333) g. Low prevalence of mild cataracts were recorded in th...

S-peptide (residues 1--14) analogues in which the active histidine-12 residue is replaced by Npi-methyl-L-histidine, Ntau-methyl-L-histidine and beta-(pyrid-3-yl)-L-alanine were synthesized and tested for their capacity to bind to S-protein and to activate it. The results show that both imidazolyl nitrogen atoms are required for optimal catalytic functioning, Ntau being essential to the catalyt...

Atopic dermatitis (AD), also known as eczema, is one of the most common chronic skin conditions worldwide, affecting up to 16% of children and 10% of adults. It is incurable and has significant psychosocial and economic impacts on the affected individuals. AD etiology has been linked to deficiencies in the skin barrier protein, filaggrin. In mammalian skin, l-histidine is rapidly incorporated i...

l-Histidine and, to a lesser degree, l-phenylalanine at concentrations of 10(-4)m inhibit the growth of leaky mutants (bradytrophs) of Bacillus subtilis that are deficient in the synthesis of p-hydroxyphenylpyruvate, the first intermediate specific to tyrosine synthesis. The inhibition can be overcome by growth factor amounts of l-tyrosine and p-hydroxyphenylpyruvate. Histidine and phenylalanin...

DNAzyme cascades activated by Pb(2+)- or L-histidine-dependent DNAzymes yield the horseradish peroxidase-mimicking catalytic nucleic acids that enable the colorimetric or chemiluminescence detection of Pb(2+) or L-histidine.

Organometallic complexes offer potential for design as anticancer drugs. A quantitativemodel that discriminates anticancer compounds from the inactive ones in a training series wasEquilibrium of the reaction of molybdenum (VI) with l-histidine have been studiedin aqueous solutions at pH range of 4-8, using spectrophotometry and optical rotationmethods at constant ionic strength of 0.15 mol.lit-...

Tarlow, M. J., Seakins, J. W. T., Lloyd, J. K., Matthews, D. M., Cheng, B., and Thomas, A. J. (1972). Archives of Disease in Childhood, 47, 798. Absorption ofamino acids and peptides in a child with a variant of Hartnup disease and coexistent coeliac disease. A child with a variant of Hartnup disease and coexistent coeliac disease is described. Oral tolerance tests with L-histidine, L-tyrosine,...