نتایج جستجو برای: known rock
تعداد نتایج: 757271 فیلتر نتایج به سال:
Rock art is the best known evidence of the Saharan fragile heritage. Thousands of engraved and painted artworks dot boulders and cliffs in open-air sites, as well as the rock walls of rockshelters and caves located in the main massifs. Since its pioneering discovery in the late 19th century, rock art captured the imagination of travellers and scholars, representing for a long time the main aim ...
Rho-associated kinase (ROCK) regulates neural cell migration, proliferation and survival, dendritic spine morphology, and axon guidance and regeneration. There is, however, little information about whether ROCK modulates the electrical activity and information processing of neuronal circuits. At neonatal stage, ROCKα is expressed in hypoglossal motoneurons (HMNs) and in their afferent inputs, w...
The serine/threonine kinases ROCK1 and ROCK2 are direct targets of activated rho GTPases, and aberrant rho/ROCK signaling has been implicated in a number of human diseases. We have developed novel methods for high-throughput assays of ROCK inhibitors that provide for quantitative evaluation of the ability of small molecules to inhibit the function of ROCK kinases in intact cells. Conditions for...
Supervisory Soil Scientist, Rocky Mountain Forest and Range Experiment Station, Tempe, Arizona; and Soil Microbiologist, Pacific Southwest Forest and Range Experiment Station, Glendora, California. The weathering of parent rock may be an important source of some nutrients. The rates of weathering of the different parent rock materials vary and affect the inherent fertility and productivity of a...
The Spirit landing site in Gusev Crater on Mars contains dark, fine-grained, vesicular rocks interpreted as lavas. Pancam and Mini-Thermal Emission Spectrometer (Mini-TES) spectra suggest that all of these rocks are similar but have variable coatings and dust mantles. Magnified images of brushed and abraded rock surfaces show alteration rinds and veins. Rock interiors contain </=25% megacrysts....
Some of the geotechnical parameters used in the analysis may not be accurately measured directly from laboratory tests due to effects of sample disturbance and errors of tests. The back analysis or the observational method are thus often applied to determine the representative and/or dominant strength parameters based on field observations in practice. Based on the Hoek-Brown failure criterion,...
The CC chemokine eotaxin plays a pivotal role in local accumulation of eosinophils. Very little is known about the eotaxin signaling in eosinophils except the activation of the mitogen-activated protein (MAP) kinase family. The p21 G protein Rho and its substrate Rho-associated coiled-coil forming protein kinase (ROCK) regulate the formation of stress fibers and focal adhesions. In the present ...
Based on the kinematic approach of limit analysis, a full set of upper bound solutions for the stability of homogeneous rock slopes subjected to tension cracks are obtained. The generalized Hoek-Brown failure criterion is employed to describe the non-linear strength envelope of rocks. In this paper, critical failure mechanisms are determined for cracks of known depth but unspecified location, c...
Rho kinase (ROCK), a downstream effector of Rho GTPase, is a serine/threonine protein kinase that regulates many crucial cellular processes via control of cytoskeletal structures. The C-terminal PH-C1 tandem of ROCKs has been implicated to play an autoinhibitory role by sequestering the N-terminal kinase domain and reducing its kinase activity. The binding of lipids to the pleckstrin homology (...
In this research, the relationship between P-wave velocity (Vp) and Electrical Resistivity (ER) parameters with rock mass quality indices is investigated; parameters such as rock mass quality classification (Q) and modified system for sedimentary rocks, known as Qsrm. For making predictive models, about 1200 data-sets extracted from sections drilled in Seymareh and Karun 2 Dam Sites (SDS and KD...
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