The human leukemia cell lines HL-60, KG-1, KLM-2, ML-3, THP-1, and U-937 were treated with the phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA). TPA partially or completely inhibited the proliferative activity of the cell cultures. The number of cells with the ability to reduce nitroblue tetrazolium increased in the TPA-treated cell lines HL-60, ML-3, THP-1, and U-937, whereas the cell ...

A stable diode pumped Kerr-lens mode-locked (KLM) Yb:LuYSiO5 (Yb:LYSO) laser of generating 61 fs pulses at a central wavelength of 1055.4 nm is experimentally demonstrated. This is, to the best of our knowledge, the first demonstration of femtosecond KLM operation in Yb:LYSO laser, and it is believed that 61 fs is the shortest pulse duration ever produced from an Yb-doped orthosilicate laser. T...

We demonstrate a self-starting Kerr-lens mode-locked (KLM) Yb:YAG thin-disk oscillator operating in the regime of positive intracavity group-delay dispersion (GDD). It delivers 1.7 ps pulses at an average power of 17 W and a repetition rate of 40 MHz. Dispersive mirrors compress the pulses to a duration of 190 fs (assuming sech2 shape; Fourier limit: 150 fs) at an average power level of 11 W. T...

The Capacitated Vehicle Routing Problem is a much-studied (and stronglyNP-hard) combinatorial optimization problem, for which many integer programming formulations have been proposed. We present two new multi-commodity flow (MCF) formulations, and show that they dominate all of the existing ones, in the sense that their continuous relaxations yield stronger lower bounds. Moreover, we show that ...

The Keystroke-Level Model (KLM) is a model for predicting the execution time of routine tasks. Initially, it had been devised for standard keyboard-desktop settings but an extension of this model for interactions with mobile phones has been described by Holleis et al. [10]. We propose a considerable update of this KLM focusing on NFC-based applications and interactions which are continuously ga...

We present efficient and robust Kerr-lens mode locking (KLM) of a diode-pumped Cr:LiSAF laser using a gain-matched output coupler (GMOC). An inexpensive, battery-powered 660 nm single-spatial-mode diode was used as the pump source. GMOC enhances the effective self-amplitude modulation depth by reducing the gain-filtering effect in broadband KLM operation to provide significant improvement in ef...

Passive mode-locking critically relies on a saturable loss mechanism to form ultrashort pulses. However, in Kerr-lens (KLM), no actual absorption takes place, but rather losses appear due diffraction, and light must escape the cavity. The effect works generate through diffraction an effective instantaneous absorber that delicately depends interplay between spatial temporal profiles of pulse. De...