نتایج جستجو برای: kisspeptins
تعداد نتایج: 148 فیلتر نتایج به سال:
objective(s): ghrelin is a peptide hormone that has been shown to have numerous central and peripheral effects. the central effects including gh secretion, food intake, and energy homeostasis are partly mediated by kiss1- kissr signaling pathway. ghrelin and its receptor are also expressed in the pancreatic islets. ghrelin is one of the key metabolic factors controlling insulin secretion from t...
Spermatogenesis, the process that leads the production of male gametes, consists in the progression of mitotic spermatogonia toward meiosis and spermiogenesis in order to produce functional spermatozoa. This complex process requires a deep network among a wide set of endocrine, paracrine and autocrine factors exerting their activity at different levels along the hypothalamus-pituitary-gonad (HP...
Prolactin is best known for its effects of stimulating mammary gland development and lactogenesis. However, prolactin is a pleiotropic hormone that is able to affect several physiological functions, including fertility. Prolactin receptors (PRLRs) are widely expressed in several tissues, including several brain regions and reproductive tract organs. Upon activation, PRLRs may exert prolactin's ...
The present study investigated whether kisspeptin-G protein-coupled receptor 54 (GPR54) signaling plays a role in mediating mating-induced ovulation in the musk shrew (Suncus murinus), a reflex ovulator. For this purpose, we cloned suncus Kiss1 and Gpr54 cDNA from the hypothalamus and found that suncus kisspeptin (sKp) consists of 29 amino acid residues (sKp-29). Injection of exogenous sKp-29 m...
Neurons that produce gonadotropin-releasing hormone (GnRH) reside in the basal forebrain and drive reproductive function in mammals. Understanding the circuitry that regulates GnRH neurons is fundamental to comprehending the neuroendocrine control of puberty and reproduction in the adult. This review focuses on a family of neuropeptides encoded by the Kiss1 gene, the kisspeptins, and their cogn...
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