BACKGROUND Candida albicans has been the most common cause of fungal bloodstream infections (BSIs) in intensive care units (ICUs); however, infections due to non-albicans Candida species have been increasing in prevalence. We examined factors associated with BSIs due to non-albicans Candida species, compared with C. albicans BSIs, in an ICU patient population. METHODS For our case-comparator ...

Candida albicans is an opportunistic human pathogen causing both superficial and disseminated diseases. It is a dimorphic fungus, switching between yeast and hyphal forms, depending on cues from its microenvironment. Hyphae play an important role in the pathogenesis of candidiasis. The host's response to Candida infection is multifaceted and includes the participation of granulocytes as key eff...

Aim: Candida is one of the most common opportunistic fungi in HIV/AIDS cases. A detailed knowledge about oral candida carriage in HIV seropositive individuals is of paramount importance in the treatment of Oral Candidiasis (OC). In the present work, our aim was to determine and compare the candida carriage rate both in HIV infected and HIV non-infected healthy individuals along with knowing the...

background and purpose: candida species are the most opportunistic fungi affecting the nails and resulting in onychomycosis. in this study, we identified and evaluated in-vitro susceptibility of the recovered isolates against fluconazole (flc), voriconazole (vrc), and clotrimazole (clt) using the clinical and laboratory standards institute (clsi) m27-a3 document. materials and methods: from pat...

Three surgery patients were monitored postoperatively, with particular reference to lung infection. In each case there was a clinical impression that Pseudomonas aeruginosa suppressed the growth of Candida albicans in patients with clinically significant lung infections from whom both of these organisms were isolated from serial sputum samples. Regrowth of C. albicans after P. aeruginosa eradic...

background and aims. it is believed that adherence of candida albicans to oral surfaces is a critical event in the colonization and development of oral diseases such as candida-associated denture stomatitis. although there is considerable information about the adherence of candida albicans to buccal epithelial cells and prosthetic materials, there is very little information available about the ...

background: natural products are proved to play a good role as an alternative to synthetic chemicals in clinical conditions. previous studies showed that pelargonium graveolens has anti-inflammatory and antifungal activity against candida albicans . the aim of this study was to evaluate the efficacy of essential oil of pelargonium graveolens in the treatment of denture stomatitis . materials an...

a radio assay employing 14c-uridine to measure the intracellular killing of candida albicans by phagocytes is presented. the principle of this new method is that after killing of candida albicans by phagocytes rna synthesis stops and therefore uridine uptake is diminished whilst viable candida in cultures would take up uridine and as a result, high cpm counts can be obtained within 135 min. of ...

This study was conducted to determine the proteinase, phospholipase, and biofilm forming abilities of Candida isolates in blood cultures of specimens from patients at the University Malaya Medical Center, Kuala Lumpur, Malaysia. Proteinase and phospholipase activities were detected in 93.7% and 73.3%, respectively, of 15 Candida albicans isolates. Amongst the 26 non-C. albicans Candida isolates...

The fungal pathogen Candida albicans is an opportunistic fungal pathogen that causes oral and vaginal mucosal infections as well as systemic disease. The ability of C. albicans to adhere to host surfaces is positively correlated with its pathogenicity. We prepared a polyclonal anti-Candida albicans antibody in chicken egg yolk (anti-C. albicans IgY) and investigated its in vitro effectiveness i...