نتایج جستجو برای: keratinization disorders
تعداد نتایج: 671844 فیلتر نتایج به سال:
Darier’s disease results from abnormal keratinization of skin and is characterized by numerous keratotic papules that preferentially involve seborrheic areas. Kaposi’s varicelliform eruption (KVE) occurs by viral infections such as herpes simplex virus (HSV) in some inflammatory skin disorders like Darier’s disease. Herein, we describe a 68-year-old man, a known case of Darier’s disease, who pr...
Mutations in ceramide biosynthesis pathways have been implicated in a few Mendelian disorders of keratinization, although ceramides are known to have key roles in several biological processes in skin and other tissues. Using whole-exome sequencing in four probands with undiagnosed skin hyperkeratosis/ichthyosis, we identified compound heterozygosity for mutations in KDSR, encoding an enzyme in ...
OBJECTIVE To compare the degree of keratinization of buccal mucosa between nonsmoking menstruating and postmenopausal women without oral complaints whose iron status was established. STUDY DESIGN Samples collected from 26 nonsmoking, regularly menstruating women (mean age, 26 years) and 18 nonsmoking, postmenopausal women without oral complaints (mean age, 57 years) were stained according to ...
Hereditary ichthyosis is a group of generalized hereditary keratinization disorders characterized by general dryness the skin, peeling, hyperkeratosis and often erythroderma. These manifestations are caused mutations in genes mainly involved formation skin barrier. divided into syndromic non-syndromic. Nonsyndromic ichthyoses include: vulgar ichthyosis, recessive X-linked autosomal congenital k...
IMPORTANCE Keratinization is a histologic feature on hematoxylin-eosin staining associated with adverse outcomes in head and neck cancer, particularly oral cavity squamous cell carcinoma. However, the prognostic value of keratinization has not been demonstrated in oropharyngeal squamous cell carcinoma (OPSCC) in a large cohort of patients. OBJECTIVE To quantify the prognostic value of keratin...
monolayer cultures were first prepared with the tubes in conventional horizontal position. When cultures were then changed to a vertical position, stratification, piling up, and aggregation of cells were observed in a few days at the aerobic end of the gradient. Keratinization appeared 1 week after the tubes were placed in vertical position. Squamous differentiation proceeded to the formation o...
© 2010 The Authors. doi: 10.2340/00015555-0800 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Porokeratosis (PK) is a heterogeneous group of hereditary or acquired disorders of keratinization with a broad clinical spectrum and various aetiologies. Common to all PK is the typical histological feature of a cornoid lamella, which corresponds to the hyperkeratotic rim of...
DSAP: Disseminated superficial actinic porokeratosis DSP: Disseminated superficial porokeratosis INTRODUCTION The porokeratoses are a group of disorders of abnormal epidermal keratinization resulting in the characteristic histologic feature of the cornoid lamella. Several clinical variants of porokeratosis exist, which are unified by this common histologic feature but differ in morphology, dist...
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