نتایج جستجو برای: karyotype test

تعداد نتایج: 821326  

2017
Gian Matteo Rigolin Luca Formigaro Maurizio Cavallari Francesca Maria Quaglia Enrico Lista Antonio Urso Emanuele Guardalben Sara Martinelli Elena Saccenti Cristian Bassi Laura Lupini Maria Antonella Bardi Eleonora Volta Elisa Tammiso Aurora Melandri Massimo Negrini Francesco Cavazzini Antonio Cuneo

We investigated whether karyotype analysis and mutational screening by next generation sequencing could predict outcome in 101 newly diagnosed chronic lymphocytic leukemia patients with high-risk features, as defined by the presence of unmutated IGHV gene and/or 11q22/17p13 deletion by FISH and/or TP53 mutations. Cytogenetic analysis showed favorable findings (normal karyotype and isolated 13q1...

M Nasri S Dorafshan Y Keivany,

In this study, for the first time in Iran, the karyotype of bigmouth Lotak, Cyprinion macrostomum Heckel, 1843, was investigated through examining metaphase chromosomes of seven fish with mean weight 30±5g caught by electrofishing from Godarkhosh River in Ilam Province. To stimulate cell divisions, fish were injected intraperitoneally two times by phytohemagglutinin (PHA). The cell divisions we...

Journal: :International journal of clinical and experimental medicine 2015
Wei-Lin Ke Wei-Hua Zhao Xin-Yu Wang

OBJECTIVE The study aimed to validate the efficacy of detection of fetal cell-free DNA in maternal plasma of trisomy 21, 18 and 13 in a clinical setting. METHODS A total of 2340 women at high risk for Down syndrome based on maternal age, prenatal history or a positive sesum or sonographic screening test were offered prenatal noninvasive aneuploidy test. According to the prenatal noninvasive a...

2012
Hongxiu Wen Yongjin Li Sami N. Malek Yeong C. Kim Jia Xu Peixian Chen Fengxia Xiao Xin Huang Xianzheng Zhou Zhenyu Xuan Shiva Mankala Guihua Hou Janet D. Rowley Michael Q. Zhang San Ming Wang

Genetic aberrations contribute to acute myeloid leukemia (AML). However, half of AML cases do not contain the well-known aberrations detectable mostly by cytogenetic analysis, and these cases are classified as normal karyotype AML. Different outcomes of normal karyotype AML suggest that this subgroup of AML could be genetically heterogeneous. But lack of genetic markers makes it difficult to fu...

2015
Kaan Savasoglu Kadriye Bahriye Payzin Fusun Ozdemirkiran Belgin Berber

Objective: To determine the use of the Quantitative Real Time PCR (RQ-PCR) assay follow-up with Chronic Myeloid Leukemia (CML) patients. Study Design: Cross-sectional observational. Place and Duration of Study: Izmir Ataturk Education and Research Hospital, Izmir, Turkey, from 2009 to 2013. Methodology: Cytogenetic, FISH, RQ-PCR test results from 177 CML patients' materials selected between 200...

Journal: :The Journal of Sexual Medicine 2023

Abstract Introduction Microdeletions of the Y-chromosome (Yq) and karyotype abnormalities are frequent causes male factor infertility. Current AUA/EUA guidelines recommend obtaining Yq microdeletion analysis, karyotype, genetic counseling in men with non-obstructive azoospermia or severe oligospermia (<5 mil/mL). A recent retrospective cohort study suggests that microdeletions primarily ...

Journal: :International journal of advanced research 2021

Crinum asiaticum L. and latifolium are members of the family Amaryllidaceae. Karyomorphological studies these two species had been performed by using different quantitative qualitative parameters to know karyotype asymmetry, which defines advanced primitive nature species. The study revealed that diploid with 2n=22 chromosomes. based on Total Chromatin Length, Arm Ratio, Gradient Index, Form Pe...

Journal: :Pediatrics 2010
Yiping Shen Kira A Dies Ingrid A Holm Carolyn Bridgemohan Magdi M Sobeih Elizabeth B Caronna Karen J Miller Jean A Frazier Iris Silverstein Jonathan Picker Laura Weissman Peter Raffalli Shafali Jeste Laurie A Demmer Heather K Peters Stephanie J Brewster Sara J Kowalczyk Beth Rosen-Sheidley Caroline McGowan Andrew W Duda Sharyn A Lincoln Kathryn R Lowe Alison Schonwald Michael Robbins Fuki Hisama Robert Wolff Ronald Becker Ramzi Nasir David K Urion Jeff M Milunsky Leonard Rappaport James F Gusella Christopher A Walsh Bai-Lin Wu David T Miller

BACKGROUND Multiple lines of evidence indicate a strong genetic contribution to autism spectrum disorders (ASDs). Current guidelines for clinical genetic testing recommend a G-banded karyotype to detect chromosomal abnormalities and fragile X DNA testing, but guidelines for chromosomal microarray analysis have not been established. PATIENTS AND METHODS A cohort of 933 patients received clinic...

Journal: :Human reproduction 2012
Mayumi Sugiura-Ogasawara Yasuhiko Ozaki Kinue Katano Nobuhiro Suzumori Tamao Kitaori Eita Mizutani

BACKGROUND We previously found that a normal karyotype in a previous miscarriage is a predictor of subsequent miscarriage. However, the prevalence of recurrent miscarriage caused by an abnormal embryonic karyotype has not yet been reported, since embryonic karyotype is not typically analyzed during conventional examinations. METHODS A total of 482 patients who underwent both embryonic karyoty...

Journal: :Biomedical research and clinical reviews 2022

It is considered that the main distinguishing feature of Homo sapiens from other living beings presence his mind. There are many hypotheses regarding origin human The complexity problem lies in fact it impossible to experimentally test any existing hypotheses. Perhaps we will never fully know how mind arose, but necessary strive for this. Here discuss possible causes a large brain modern man, i...

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