KAPosI multiple idiopathic haemorrhagic sarcoma is a peculiar condition which cannot be accurately classified (Reese, 1963). It was regarded by Kaposi (1872) as a cutaneous sarcoma affecting the blood vessels; by Ewing (1922) as an infectious granuloma; by Pautrier and Diss (1928) as originating from nerve tissue; and by D6rffel (1932) as arising from the reticulo-endothelial system, the lesion...

Kaposi sarcoma-associated herpesvirus infection is associated with the development of 3 proliferative diseases: Kaposi sarcoma, primary effusion lymphoma, and multicentric Castleman disease. These conditions are also intimately associated with human immunodeficiency virus infection, and important synergistic interactions between these 2 viruses have been described. Despite differences in viral ...

Kaposi sarcoma is a low-grade mesenchymal tumor involving blood and lymphatic vessels. There are four variants of this disease, each presenting a different clinical manifestation: classic or sporadic, African or endemic, organ transplant-related or iatrogenic, and AIDS-related or epidemic. Kaposi sarcoma is the most common tumor among patients with HIV infection, occurring predominantly in homo...

kaposiform hemangioendothelioma is an aggressive endothelial-derived spindle cell neoplasm that occurs nearly exclusively during childhood and teenage years. the lesion grows rapidly and is often associated with kasabach-merritt syndrome. in this study a 24 days old male neonate who presented with an ill-defined deeply situated violaceous mass on his left arm is described. he had also anemia an...

A 63-year-old woman with long-standing AIDS and previous Kaposi sarcomas of the lower limb presented to our consultation complaining of a painful left ring finger with pulp enlargement. X-rays revealed an osteolytic lesion of the distal phalanx. We suspected an isolated osseous Kaposi sarcoma and at surgery we found a hemorrhagic lesion with bone extension into the phalanx. Bone involvement is ...

BACKGROUND The penis is an unusual site of presentation for Kaposi sarcoma, especially in immunocompetent patients. CASE PRESENTATION A 52-year-old human immunodeficiency virus (HIV)-seronegative man presented with a reddish, 8 mm in diameter nodule on the glans penis near the coronal sulcus. Histopathology after excision of the lesion was consistent with Kaposi sarcoma. No other cutaneous or...

Kaposi sarcoma remains an important cause of morbidity in HIV-infected patients. Regardless of the recent pharmacological progress, treatment of this malignancy is still disappointing. We report the case of a patient with Kaposi sarcoma in an unusual localization, the penis, which completely resolved with highly active antiretroviral therapy alone.

OBJECTIVE Kaposi sarcoma is an angioproliferative disease. Kaposi sarcoma is clinicopathologically classified into four subgroups based on epidemiological data. For its systemic treatment, in addition to some chemotherapeutics, taxanes have also been used during the recent years for their anti-angiogenic properties. In this study, we aimed to compare paclitaxel and non-paclitaxel chemotherapeut...

A 47-year-old heterosexual man with history of intravenous (IV) methamphetamine use presented to the Emergency Department dyspnea and raised lesions throughout his arms, legs, chest as depicted in Figure 1. Biopsy a right leg lesion demonstrated atypical vascular proliferation within dermis producing slit-like/irregular architecture consistent Kaposi sarcoma. Human herpesvirus 8 (HHV-8) stainin...

AIM Since most forms of Kaposi sarcoma are much more common in men than in women, the aim of this study was to examine serum concentrations of sex steroids in HIV positive men with and without Kaposi sarcoma. METHODS Blood samples from 34 HIV positive men without Kaposi sarcoma (KS-) and 28 with Kaposi sarcoma (KS+) and from 35 HIV negative men (controls) were analysed for adrenal and gonadal...