BACKGROUND AND PURPOSE The aim of this nationwide cohort study was to evaluate whether the occurrence of isolated 3rd, 4th or 6th cranial nerve (CN) palsies is associated with a higher risk of ischemic stroke. METHODS This study utilized data from Taiwan Longitudinal Health Insurance Database during 1995-2012. Subjects aged 20 years or older who had isolated CN 3/4/6 palsies diagnosed by a ne...

2-Cyanobenzofurans and 2-cyanobenzothiophenes were prepared through an efficient one-pot Ullmann-reaction/cyanation reaction. In the presence of CuI/Na(2)CO(3)-Pd(OAc)(2)/PPh(3) in DMF, the reaction of 2-(gem-dibromovinyl)phenols and 2-(gem-dibromovinyl)thiophenols with K(4)Fe(CN)(6), as non-toxic and user-friendly cyanating reagent, proceeded smoothly to generate the corresponding 2-cyanobenzo...

A finite-difference method for predicting the current-density distribution in multi-ion electrolytes was developed, then implemented to actual experimental systems and compared with other numerical methods, analytic solutions for limiting conditions, and experimental measurements in order to be tested. The method accounted for diffusion, ionic migration, laminar convection, and heterogeneous el...

A summary of photo- and electrochemical surface modifications applied on single-crystalline chemical vapour deposition diamond films is given. The covalently bonded formation of amine and phenyl linker molecular layers is characterized using X-ray photoelectron spectroscopy, atomic force microscopy (AFM), cyclic voltammetry and field-effect transistor characterization experiments. Amine and phe...

BACKGROUND The increasing numbers of people who use plant-based remedies as alternative or complementary medicine call for the validation of less known herbal formulations used to treat their ailments. Since Puerto Rico has the highest rate of Type 2 diabetes within all the states and territories of the United States, and Puerto Ricans commonly use plants as diabetes adjuvants, it is important ...

Formation of the ferryl (FeIV=O) porphyrin radical cation known as Compound I in the reaction of horseradish peroxidase (HRP) with H2O2 is catalyzed by His-42, a residue that facilitates the binding of H2O2 to the iron and subsequent rupture of the dioxygen bond. An H42A mutation was shown earlier to decrease the rate of Compound I formation by a factor of approximately 10(6) and of guaiacol ox...

In a previous paper (George & Irvine, 1954a) we concluded that there are two kinds of structure for the higher oxidation state of metmyoglobin (MetMb) which could explain the experimental observations. One is a radical structure formed by hydrogen atom removal from a methine carbon atom, a pyrrolic carbon atom or some other atom within the conjugated network of porphyrin ring and haemoprotein l...