Background: Rheumatoid arthritis (RA) and juvenile rheumatoid arthritis (JRA) are systemic autoimmune diseases characterized by synovitis and a wide range of extra articular manifestations. Ocular involvement occurs frequently in both diseases and it may affect all layers. Objectives: To identify different types of ocular involvement in cases of Adult Rheumatoid Arthritis (RA) and Juvenile Rheu...

Arthritis is a chronic inflammatory disease with an interaction of various genetic and environmental factors. It is a heterogenous group of disorder with different etiological and pathogenetic mechanisms. Lipid peroxidation is the prevailing mechanism in various inflammatory disorders. Hence the present study is aimed at evaluating the status of pro and antioxidants in the etiology of arthritis...

소아기 류마티스 관절염은 소아에서 가장 흔히 발병하는 류마 티스 질환으로 진단의 정의는 16세 미만에서 시작된 적어도 6주 이상 지속된 특발성 관절염이다 1) . 이 질환은 하나의 질병이라기 보다는 만성 염증성 관절염의 다양한 형태로 설명되고 있다. 소아 기 류마티스 관절염은 성인에서 볼 수 있는 류마티스 관절염과는 원인, 병의 경과 및 예후 등 여러 가지 면에 있어서 차이가 있기 때문에 소아기 라는 말이 붙어 있다. 관절염이란 용어는 부종 또는 통증과 움직임의 제약이 적어도 한 관절 이상에서 관찰될 때 적용된다 2) . 그런데 침범되는 관절의 부위와 수, 전신 증상의 존재 여부, 합병증 및 예후 등이 환자마다 다양하게 나타나기 때문에 이제까지는 발병 후 처음 6개월 내에 나타나는 증상을 바탕으로 하여...

The presentation of juvenile psoriatic arthritis (JPsA) has long been recognized to be clinically heterogeneous. As the definition of JPsA expanded to accommodate atypical manifestations of psoriasis in young children, studies began to reflect an increasingly clear biphasic distribution of age of onset, with peaks in the first few years of life and again in early adolescence. These two subpopul...

Seven out of 22 children with monarticular juvenile rheumatoid arthritis (MJRA) developed involvement of other joints between six months and three and a half years from the onset. In the other 15 patients the disease has remained monarticular for between one and 16 years (mean six years). Chronic iridocyclitis was seen in three of the five boys, two with antinuclear antibodies. Children with MJ...

Chronic childhood arthritis affecting more than four joints during the first 6 months of disease is defined as polyarthritis.1,2 In the classification of the International League of Associations for Rheumatology (ILAR),2 polyarthritis is further categorized as rheumatoid factor (RF) negative if tests for RF are negative, and RF positive if RF is detected on two occasions at least three months a...

The clinical course of children with IgM rheumatoid-factor-positive chronic arthritis closely resembles that of seropositive rheumatoid disease in adults. The frequency of HLA DR4 is known to be increased in adults with seropositive rheumatoid arthritis, but the first major report on childhood arthritis did not suggest a correlation, though only 8 seropositive cases were included. Fifty-two chi...

Juvenile rheumatoid arthritis (JRA) differs in many aspects from its adult counterpart (Edstrom, 1958); one of the differences is a low incidence of positive sero-reactions for rheumatoid factors (RF) in patients with JRA (Bywaters, Carter, and Scott, 1959; Sievers, Ahvonen, Aho, and Wager, 1963; Ansell, 1966). Although the agglutinating activity of RF was found in different classes of immunogl...