It is not widely appreciated how deleterious prolonged periods of non-weight-bearing are to skeletal integrity. Rates of decline in humans exposed to prolonged spaceflight, for example, are about 10-fold greater than those observed in postmenopausal women and are associated with a significant loss of bone strength. New data on the efficacy of muscle contraction independent of weight bearing in ...

BACKGROUND Although bone mineral density (BMD) testing to screen for osteoporosis (BMD T score, -2.50 or lower) is recommended for women 65 years of age or older, there are few data to guide decisions about the interval between BMD tests. METHODS We studied 4957 women, 67 years of age or older, with normal BMD (T score at the femoral neck and total hip, -1.00 or higher) or osteopenia (T score...

1. Discuss the risks of placing implant-supported restorations in patients with aggressive periodontitis. 2. Detail the research conducted on implant success and failure in patients with aggressive periodontitis. 3. Identify the restorative options for patients with aggressive periodontitis. 4. Explain the proper implant maintenance protocol for patients at increased risk of implant complicatio...

osteopenia of prematurity (oop) is a preventable disease. improved survival of premature newborns is associated with an increased incidence of oop. the purpose of this study was to compare the prophylactic effects of two low doses of vitamin d (200 and 400 iu/day) on the clinical, biochemical and radiological indices of the rickets of prematurity. in a randomized clinical trial, 60 preterm newb...

Objectives Multiple studies have documented the presence of systemic osteopenia in AIS. Osteopenia was associated with severe curves and was reported to be one of the significant prognostic factors for curve progression in AIS. This study aimed to evaluate bone quality and bone strength parameters including rod-plate configuration and finite element analysis (FEA) with in vivo HighResolution Pe...

BACKGROUND Bony augmentation of the anterior glenoid is used in athletes with recurrent shoulder instability and bone loss; however, the prevalence and impact of repair in elite American football athletes are unknown. PURPOSE To evaluate the prevalence and impact of glenoid augmentation in athletes invited to the National Football League (NFL) Scouting Combine from 2012 to 2015. STUDY DESIG...

Genetic factors have an important role in the incidence of osteopenia in thalassemia patients. The purpose of this study was to investigate the effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-γ (PPARγ) gene on bone mineral density (BMD) and subsequently, the rate of osteopenia in β-thalassemia major (β-TM) patients. Blood samples were obtained from 156 β-TM...

Therapeutic effects of mesenchymal stem cell (MSC) infusion have been revealed in various human disorders, but impacts of diseased micro-environments are only beginning to be noticed. Donor diabetic hyperglycemia is reported to impair therapeutic efficacy of stem cells. However, whether recipient diabetic condition also affects MSC-mediated therapy is unknown. We and others have previously show...

Background: Decrease in bone mineral density (BMD) is common individuals infected with human immune deficiency virus (HIV) and the rate of osteopenia, osteoporosis fracture risk are higher than gene-ral population. In our study, we aimed to evaluate frequency osteoporosis/osteopenia according results dual-energy X-ray absorptiometry (DXA) examination associated factors also 25 (OH) vitamin D.Ma...