The authors compared self-reported occupational exposures with a workplace-specific job exposure matrix (JEM) in a 2004 survey of Texas health-care professionals (n = 3,650), by asthma status. Sensitivity, specificity, chance-corrected (kappa) and chance-independent (phi) agreement, and associations of self-reported exposures with asthma were compared with those for the JEM. Among asthmatics, t...

In this issue of JEM, Wu et al. (https://doi.org/10.1084/jem.20171341) use genetic barcoding of macaque hematopoietic stem cells to demonstrate that, after transplantation, HSCs are very asymmetrically distributed and uncover a thymus-independent pathway for mature T cell production in the bone marrow.

We are starting the New Year with an updated look and new content. The JEM has never been fashion conscious, and its distinctive format has changed very little over 109 years. It is an advantage to be instantly recognizable amidst the sea of PDF printouts found on most scientists' desks, so we have preserved the essential look of the Articles and Brief Definitive Reports. The new design is, how...

The Java Embedded Micro-kernel (JEM) architecture is an object-oriented execution environment for small devices with limited system resources, such as intelligent network cards or PDAs. The core of the architecture is a Java-based micro-kernel providing a framework for dynamically loading service modules onto embedded devices at runtime and mechanisms for interconnecting these service modules t...

J. E. Moeslund ([email protected]), P. K. B ø cher and J.-C. Svenning, Ecoinformatics and Biodiversity Group, Dept of Bioscience, Aarhus Univ., Ny Munkegade 114, DK-8000 Aarhus C, Denmark. – JEM and L. Arge, Center for Massive Data Algorithmics (MADALGO), Dept of Computer Science, Aarhus Univ., IT-parken, Å bogade 34, DK-8200 Aarhus N, Denmark. – JEM and T. Dalgaard, Agricultural Sy...

In this issue of JEM, Marciniak et al. (https ://doi .org /10 .1084 /jem .20161731) identify a putative novel function of tau protein as a regulator of insulin signaling in the brain. They find that tau deletion impairs hippocampal response to insulin through IRS-1 and PTEN dysregulation and suggest that, in Alzheimer’s disease, impairment of brain insulin signaling might occur via tau loss of ...