BACKGROUND Drug injection is one of the most prominent risk factors for transmission of viral hepatitis. Prevalence of hepatitis B virus (HBV) is generally higher in prisoners compared with the general population. The object of this study was to assess the markers of HBV and related risk factors among intravenous drug users (IVDU) in prisoners. MATERIALS AND METHODS Through a cross-sectional ...

The in vitro susceptibility of eight strains of varicella-zoster virus (VZV) to E-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) was examined in human embryonic fibroblasts by the following techniques: inhibition of focus formation by either cell-free VZV (4-day assay) or cell-associated VZV (2-day assay), inhibition of viral antigen formation (2-day assay), and inhibition of viral cytopathogenicity (...

Methods We performed a retrospective study on 45 patients, intravenous drug users (IVDU), diagnosed with HIV infection between 01 December 2010 – 01 August 2013 (30 months), in our department for HIV/AIDS infection in the Clinical Hospital of Infectious and Tropical Diseases “Dr. Victor Babeş” in Bucharest. All of these patients were also diagnosed and treated for Mycobacterium tuberculosis (TB...

Intravenous drug use (IVDU) is the major risk factor in the development of HIV-related pulmonary arterial hypertension (HRPAH); however, the pathogenesis of HRPAH in association with IVDU has yet to be characterized. Endothelial injury is considered to be an initiating factor for pulmonary vascular remodeling in animal models of PAH. Our previous study shows that simultaneous exposure to HIV-Tr...

Abstract Aim This study aimed to determine the diagnostic accuracy of native joint aspirations for adult septic arthritis (SA), and clinical factors associated with a positive diagnosis SA. Method Retrospective review patients (≥16yrs) undergoing major aspiration at single centre over year period (2019) were identified. Patient demographics, biochemical data, details, post-aspiration diagnosis,...

We report a case of an intravenous drug user (IVDU) patient who had 4 episodes of endocarditis within a 2-year time period in rural Georgia. The institutional cost was approximately $380,000. The lack of an established transitional care plan for IVDUs to outpatient care is a common phenomenon at institutions. Guidelines are essential to optimize the quality of care rendered to IVDUs with such i...

BACKGROUND Little representative information exists on the frequency of human immunodeficiency virus (HIV)-related diseases among the overall AIDS population. The objective of this research is to assess the nature, frequency and characteristics of these diseases among AIDS patients during their last year of life and to analyse these frequencies according to the mode of transmission and other so...

Cellulitis and cutaneous abscess are the most common skin soft tissue infections (SSTI), accounting for 4 million emergency department (ED) visits 1.5 incision drainage (I&D) procedures. Ultrasound (US) may differentiate cellulitis from more accurately than clinical evaluation reduces inappropriate I&D procedures, unnecessary antibiotics, failure to resolve post-drainage. However, there current...

OBJECTIVE To assess efficacy, adherence and tolerability of once daily antiretroviral therapy containing tenofovir disoproxil fumarate (DF) 300 mg in HIV-1-infected former injecting drug users receiving opiate treatment (IVDU). METHODS European, 48-week, open-label, single-arm, multicenter study. Patients were either antiretroviral therapy-naive, restarting therapy after treatment discontinua...