OBJECTIVE To exam semen parameters in predicting intrauterine insemination (IUI) outcomes in couples with male factor. STUDY DESIGN This retrospective study was performed at department of infertility and sexual medicine from September 2007 to February 2014. 307 couples with male factor infertility were included and 672 IUI cycles were analyzed. RESULTS From 672 inseminations performed on 30...

OBJECTIVE To determine the optimal infertility therapy for women at the end of their reproductive potential. DESIGN Randomized clinical trial. SETTING Academic medical centers and private infertility center in a state with mandated insurance coverage. PATIENT(S) Couples with ≥ 6 months of unexplained infertility; female partner aged 38-42 years. INTERVENTION(S) Randomized to treatment w...

A previous randomized clinical trial compared immobilization for 15 min with immediate mobilization subsequent to intrauterine insemination (IUI) and showed higher ongoing pregnancy rates in couples immobilizing subsequent to IUI. The current study compared the long-term effectiveness of immobilization subsequent to IUI. All couples (n = 391) included in the trial were followed for 3 years afte...

OBJECTIVE To determine the efficacy of daily versus alternate-day stimulation for patients undergoing intrauterine insemination (IUI). DESIGN Retrospective comparative study. SETTING University tertiary care center for infertility. PATIENT(S) Women with anovulatory or unexplained infertility for over 12 months who had not responded to or not conceived with clomiphene citrate treatment. ...

BACKGROUND We recently reported that treatment with intrauterine insemination and controlled ovarian stimulation (IUI-COS) did not increase ongoing pregnancy rates compared with expectant management (EM) in couples with unexplained subfertility and intermediate prognosis of natural conception. Long-term cost-effectiveness of a policy of initial EM is unknown. We investigated whether the recomme...

OBJECTIVE To determine the risk of major birth defects in cohorts of children conceived through IVF or through IUI as compared with naturally conceived children. DESIGN Retrospective cohort study. SETTING Academic medical center. PATIENT(S) Children conceived by IVF or IUI at the University of Iowa from 1989 through 2002, compared with a matched cohort of naturally conceived children. I...

Background: Although intrauterine insemination (IUI) is one of the most common methods which is used for male factor and unexplained infertility, the relative influence of various semen parameters on the likelihood of a successful outcome is controversial. Several semen parameters have been evaluated as predictors of a successful outcome with intrauterine insemination. Objective: To evaluate th...

PURPOSE The association between tenaculum application to the cervix just before embryo transfer and lower pregnancy rate has been reported. However, studies on the use of tenaculum in intrauterine insemination (IUI) cycles are not available. This study attempted to investigate whether the use of tenaculum affects the clinical outcomes of IUI. MATERIALS AND METHODS Two hundred and thirty three...

BACKGROUND Implantation is considered as the rate-limiting step in success of assisted reproduction techniques, and intrauterine insemination cycles. It might be affected by ovarian superovulation and endometrial local scratching. OBJECTIVE This study aims to investigate the effect of local endometrial injury on the outcome of IUI cycles. MATERIALS AND METHODS In this randomized clinical tr...

ObjectiveTo identify the optimal lead follicle size for hCG trigger in clomiphene citrate (CC)–intrauterine insemination (IUI) cycles.DesignRetrospective cohort study.SettingUniversity-affiliated center.Patient(s)Patients <40 years of age with ovulatory dysfunction or unexplained infertility undergoing their first CC-IUI cycle.Intervention(s)Ovulation induction, trigger, and IUI.Main Outcome Me...