In Gamma Knife forward treatment planning, normalization effect may be observed when multiple shots are used for treating large lesions. This effect can reduce the proportion of coverage of high-value isodose lines within targets. The aim of this study was to evaluate the performance of forward treatment planning techniques using the Leksell Gamma Knife for the normalization effect reduction. W...

We describe a technique of postoperative irradiation of skin cancer using plesiotherapy with Ir192 high dose rate microSelectron afterloading system (Nucletron, Veenendaal, Netherlands). The clinically defined area is drawn on the skin and the flexible 'skin applicator' is then orientated so that the drawn skin area is encompassed within the catheter defined surface. Using a thin pewter wire, t...

BACKGROUND  In radiosurgery, the convention has been to prescribe radiation dose to a "covering isodose volume". This is presumed to be the minimum dose received by the entire tumor. Our purpose was to review our practice, assess different means of specifying a prescription isodose, and test how reliable they were in the face of various calculation methodologies. METHODS Different minimum dos...

Background: External beam radiotherapy and brachytherapy plays a vital role in the management of cancer cervix.  High dose rate brachytherapy is being presently used worldwide for the brachytherapy applications. At present, 2-Dimensional linear array detectors   are the most common QA tool used for pretreatment patient specific quality assurance in external beam radiotherapy alon...

background: palladium-103 (103pd) is a brachytherapy source for cancer treatment. the monte carlo codes are usually applied for dose distribution and effect of shieldings. monte carlo calculation of dose distribution in water phantom due to a med3633 103pd source is presented in this work. materials and methods: the dose distribution around the 103pd model med3633 located in the center of 30×30...

Introduction: Treatment with megavoltage electron beams is ideal for irradiating superficial tumors because of their limited range in tissues. However, for electron treatment of extended areas, such as the chest wall, two or more adjacent fields can be used. Abutment of these fields may lead to significant dose in homogeneities in the junction region. The aim of this study is to offer a new met...

We present results of investigations of the clinical significance of variations in the value of the 4-mm-collimator output factor, OF(4/18). Changes in treatment volume, dose-volume histograms (DVHs), and isodose distributions were studied, by varying OF(4/18) up to 20%. The variations were performed on a sample of clinical patient treatment plans for which the 4 mm collimator was used. Althoug...

background: monte carlo determination of tg-43 brachytherapy dosimetry parameters and dose distribution calculation for 131cs source model cs-1 are presented in this study. materials and methods: the dose distribution was calculated around the 131cs model cs-1 located in the center of 30 cm ×30 cm ×30 cm water, and soft tissue phantoms cube using mcnp code by monte carlo method. the percentage ...