OBJECTIVE It has been reported that leukocyte ROCK activity is elevated in patients after ischemic stroke, but it is unclear whether leukocyte ROCK activity is associated with clinical outcomes following acute stroke events. The objective of this study is to investigate if leukocyte ROCK activity can predict the outcomes in patients with acute ischemic stroke. MATERIALS AND METHODS We enrolle...

Objective(s): Black cumin (Nigella sativa) belonging to Ranunculaceae family has a long history of medicinal use in various folk and traditional systems of medicine, including Iranian traditional medicine (ITM). These valuable medicinal seeds have been used traditionally against a variety of diseases such as dyspepsia, diabetes, headache, influenza and asthma. In addition, several scientific in...

1. Abstract 2. Introduction 3. Materials and methods 3.1. Rat model of focal cerebral ischemia 3.2. Measurement of overall BER activity 3.3. Measurement of AP endonuclease activity 3.4. Measurement of DNA polymerase-beta activity 3.5. Western blot analysis 3.6. Quantitative measurement of AP sites in nuclear DNA 3.7. Detection of DNA single-strand breaks 3.8. Statistical analysis 4. Results 4.1...

conclusions pretreatment with epo and application of ipc significantly ameliorated the renal injury induced by bilateral renal ir. however, both treatments attenuated renal dysfunction and oxidative stress in kidney tissues. there were no significant differences between pretreatment with epo or application of ipc. materials and methods twenty four male wistar rats were allocated into four exper...

detection and modification of the risk factors of stroke may be the most effective strategy for preventing its often irreversible consequences. a longitudinal prospective study was implemented to evaluate the effect of several risk factors on the course of cerebrovascular disease. the study groups were composed of 3s8 normal volunteers, and 308 patients with transient ischemic attacks. the two ...

background: it has been reported that the chronic oral administration of garlic homogenate protected the rat heart from in vitro ischemic reperfusion injury. however, the biological effects of garlic juice on the heart are expected to be different from oral administration of it. objective: the present study was designed to investigate the effect of garlic juice on the isolated rat heart in isch...

Background and Purpose—The relationship between physical activity and stroke is inconclusive according to the 1996 US Surgeon General’s Report on Physical Activity and Health. Therefore, this study examined the relationship between physical activity and ischemic stroke risk among 14 575 Atherosclerosis Risk in Communities Study participants aged 45 to 64 years free of self-reported stroke and c...

BACKGROUND AND PURPOSE The relationship between physical activity and stroke is inconclusive according to the 1996 US Surgeon General's Report on Physical Activity and Health. Therefore, this study examined the relationship between physical activity and ischemic stroke risk among 14 575 Atherosclerosis Risk in Communities Study participants aged 45 to 64 years free of self-reported stroke and c...

BACKGROUND AND PURPOSE The purpose of this study was to quantitatively measure and describe the amount and pattern of physical activity in patients within the first week after acute ischemic stroke and transient ischemic attack using accelerometers. METHODS A total of 100 patients with acute ischemic stroke or transient ischemic attack admitted to our acute stroke unit wore Actical accelerome...