background: renal ischemia reperfusion (ir), one of the most important causative mechanisms of acute kidney injury, is a major clinical problem that occurs in some hospitalized patients. the aim of this study was to investigate the effects of hydroxytyrosol (ht) on renal ischemia-reperfusion injury in mice. methods: male mice were randomly assigned to three groups (n = 9): (1) sham operated, (2...

Objective(s): The objectives of the current study were to evaluate the effects of hepatic ‎ischemia/reperfusion (IR) injury on the activity of antioxidant enzymes, biochemical factors, and ‎histopathological changes in rat kidney, and to investigate the effect of crocin on IR-‎related changes. Materials and Methods: Thirty-two male Wistar rats were randomly allocated into four groups (n=8). The...

Preconditioning may find ready applicability in humans facing scheduled global cardiac ischemiareperfusion (IR) during bypass or transplantation, where such a maneuver is feasible before arrest. Our objective was to delineate and exploit the endogenous preconditioning mechanism triggered by transient ischemia (TI) and thereby attenuate myocardial postischemic mechanical dysfunction by clinicall...

Introduction: Ischemia/reperfusion (IR) injury involves a complex interrelated sequence of events. High levels of nitric oxide (NO) are generated with inducible form of nitric oxide synthase (iNOS) leading to the renal IR injury and glutathione (GSH) depletion. The present study was designed to investigate the effect of L-Nil (N6- (1-Iminoethyl)-L- lysine.hydrochloride), a selective inhibito...

objectives we aimed to perform the first such study to measure the injury incidence, severity and type as the first step in creating a badminton injury prevention program. patients and methods a prospective, longitudinal survey was conducted between april 2012 and march 2013 with 133 national tournament-level badminton players from junior high school to university in japan with the teams’ physi...

Börjesson, Anna, Andreas Norlin, Xiangdong Wang, RolandAndersson, and Hans G. Folkesson. TNF-a stimulates alveolar liquid clearance during intestinal ischemiareperfusion in rats. Am. J. Physiol. Lung Cell. Mol. Physiol. 278: L3–L12, 2000.—Intestinal ischemia-reperfusion commonly occurs in critically ill patients and may lead to the development of remote organ injury, frequently involving the lu...

Börjesson, Anna, Andreas Norlin, Xiangdong Wang, RolandAndersson, and Hans G. Folkesson. TNF-a stimulates alveolar liquid clearance during intestinal ischemiareperfusion in rats. Am. J. Physiol. Lung Cell. Mol. Physiol. 278: L3–L12, 2000.—Intestinal ischemia-reperfusion commonly occurs in critically ill patients and may lead to the development of remote organ injury, frequently involving the lu...