background and objectives: bacteria need iron for growth and most of them can actively acquire fe ions using especial iron-chelating proteins which named siderophores. we aimed to determine the frequencies of iuca, iron and irp2 genes in the uropathogenic escherichia coli (upec) isolates. we also analyzed the effects of siderophore genes beside iron supplements on growth rate of the isolates. m...

BACKGROUND Deficiencies of iron and folic acid during pregnancy can lead to adverse outcomes for the fetus, thus supplements are recommended. Adherence to current tablet-based supplements is documented to be poor. Recently a powdered form of micronutrients has been developed which may decrease side-effects and thus improve adherence. However, before testing the efficacy of the supplement as an ...

BACKGROUND Iron deficiency remains a prevalent adolescent health problem in low income countries. Iron supplementation is recommended but improvement of iron status requires good adherence. OBJECTIVES We explored factors affecting adolescent adherence to weekly iron and/or folic acid supplements in a setting of low secondary school attendance. METHODS Taped in-depth interviews were conducte...

OBJECTIVE A systematic review was conducted to analyze the tolerability of several oral iron supplements based on data obtained in available publications and to report the incidence of adverse effects (AEs) for each supplement both overall and gastrointestinal. METHODS Electronic databases - Medline, the Cochrane Library, and Embase were searched for studies published up to January 2009. Clin...

BACKGROUND Micronutrient deficiencies are common among women in low-income and middle-income countries. Data from randomised trials suggest that maternal multiple micronutrient supplementation decreases the risk of low birthweight and potentially improves other infant health outcomes. However, heterogeneity across studies suggests influence from effect modifiers. We aimed to identify individual...

OBJECTIVES We conducted a review of effectiveness of preventive treatments of iron deficiency anaemia in pregnancy in developing countries and highlighted their constraints as well as interventions required to strengthen the health services. Methods. Literature from Pubmed (MEDLINE), AJOL, Google Scholar, and Cochrane database was reviewed. RESULTS Evidence-based preventive treatment options ...

BACKGROUND Iron supplementation is recommended for pregnant women to meet their iron requirement for a healthy pregnancy. The benefits and risks of universal iron supplementation during pregnancy in malaria endemic countries are currently being debated. As part of a broader study that focused on the effect of heme/HO-1 on pregnancy outcomes in malaria in pregnancy, we determined the association...

Background: In nonmalaria regions, iron/folic acid supplementation during pregnancy protects newborns against preterm delivery and early neonatal death. Other studies from malaria-endemic areas have reported an adverse effect of iron supplements on malaria prevalence in pregnant women. Objective: We examined the association between iron/folic acid supplements and prenatal antimalaria prophylaxi...

Iron and folate depletion in pregnancy Most women are unable to meet the demands of expanding red cell mass and fetal growth in pregnancy without depleting their stores of iron,3'5 and diet, even in developed countries, contains insufficient folic acid to prevent a reduction in tissue folate concentrations.67 As a result some pregnant women become anaemic. Supplements of 30-100 mg elemental iro...