The increasing prevalence of multiple comorbidities among anemic patients with chronic kidney disease has made the use of serum ferritin and transferrin saturation more challenging in diagnosing iron deficiency. Because serum ferritin is an acute-phase reactant and because the inflammatory state may inhibit the mobilization of iron from reticuloendothelial stores, the scenario of patients with ...

Background Although chronic obstructive pulmonary disease is a known cause of secondary polycythemia with elevated erythropoietic demands in response to hypoxemia, anemia is relatively common in patients with chronic obstructive pulmonary disease and is related to increased mortality. However, little is currently known about the relationship between various iron parameters and disease severity ...

BACKGROUND Recently, hepcidin expression in adipose tissue has been described and shown to be increased in patients with severe obesity. We tried to assess the effect of obesity on hepcidin serum levels and treatment outcome of iron deficiency anemia in children. METHODS This was a case control study included 70 children with iron deficiency anemia "IDA" (35 obese and 35 non-obese) and 30 hea...

serum iron and total iron binding capacity anti percentage saturation were measured in 100 apparently normal individuals (50 men and 50 women) , the ages of the men were from ?2• 50 and of the women from 19-30, average serum iron in men was i33amgjloo ml and in women 112.5mg/ 100 ml, the average values for total iron binding ca paci ty were 306,?mg/ for men and ?90mg/ 100 rnl, for women, percen...

The aim of this study was to assess and to compare the role of HFE polymorphisms and other genetic factors in variation in iron stores. Blood samples were obtained from 3,375 adult male and female twins (age range 29-82 years) recruited from the Australian Twin Registry. There were 1,233 complete pairs (562 monozygotic and 571 dizygotic twins). Serum iron, transferrin, transferrin saturation wi...

we studied the prevalence of iron-deficiency anaemia in women of reproductive age, between 15 to 49, with a mean age of 31-56±1.34 years, attending mirzakoochak khan hospital ob. gyn. center for routine gynecological and obstetrical examination. we compa'tred mean values for the serum tests and haematological data and investigated etiological factors such as age, marital status, education, spou...

The observations that the peptide hormone gastrin interacts with transferrin in vitro and that circulating gastrin concentrations are increased in the iron-loading disorder hemochromatosis suggest a possible link between gastrin and iron homeostasis. This study tested the hypothesis that gastrin and iron status are interrelated by measurement of iron homeostasis in mice and humans with abnormal...

OBJECTIVE The aim of this work was to check the effects of antioxidant supplementation (vitamins E and C, and beta-carotene) on the basal iron status of athletes prior to and following their training and competition season (3 months). DESIGN Eighteen amateur trained male athletes were randomly distributed in 2 groups: placebo (lactose) and antioxidant supplemented (vitamin E, 500 mg/d; vitami...

BACKGROUND Gastric bypass surgery is a highly effective therapy for long-term weight loss in severely obese patients, but carries significant perioperative risks including infection, wound dehiscence, and leaks from staple breakdown. Iron status can affect immune function and wound healing, thus may influence peri-operative complications. Common mutations in the HFE gene, the gene responsible f...

The absorption of a test amount of radioactive iron during artificial saturation of the plasma iron-binding protein, by the repeated intravenous injection of small amounts of iron, was measured in three normal and four anemic dogs. The procedure had no detectable influence on the iron absorption of the normal dogs nor on that of two of the anemic dogs. Two other anemic dogs showed some suppress...