Introduction: In the present study, we investigated the role of gold-silica shell-core nanoparticle in megavoltage irradiation of MCF7 breast cancer cells.   Materials and Methods: gold-silicon oxide shell-core nanoparticles (NPs) were obtained by conjugation of gold nanoparticle with amine or thiol functionalized silica nanoparticles (AuN@SiO2 and AuS@SiO...

Gold nanoparticle assemblies possess diverse application potential, ranging from industrial nanotechnology to medical biotechnology. Because the structures and properties of assemblies are directly affected by the stabilization mechanism between the organic molecules serving as protecting ligands and the gold nanoparticle surface, it is crucial to find and investigate new stabilization mechanis...

in this paper, we have described the size-controlled synthesis of gold nanoparticles based on the reduction of au3+ (haucl4 ) using molybdophosphoric acid (h3[pmo12o40 ], hpmo) under uv-irradiation. in the process, hpmo plays the role of photocatalyst, reducing agent and stabilizer and propan-2-ol acts as a sacrificial agent. this method allows the synthesis of uniform hexagonal nanoparticles w...

objective(s):   this study aimed to address the gold nanoparticle(gnp)-dose and exposure duration effect on the kidney function of rats: in vivo.   materials and methods: a total of 32 healthy male wistar rats were used in this study. animals were randomly divided into groups, three gnp-treated groups and control group. group 1, 2 and 3 received. /5 cc of solution containing 5, 10,100 ppm au vi...

gold nanoparticles were synthesized by chemical reduction of haucl4 inside the pores of a polycarbonate-based membrane followed by dissolving the membrane in dichloromethane and further sonication. sonication time as the main affecting factor on the nanoparticle size was investigated. the characterization by transmission electron microscopy showed the formation of gold nanoparticles with diamet...

The engineering of responsive multifunctional delivery systems that combine therapeutic and diagnostic (theranostic) capabilities holds great promise and interest. We describe the design of thermosensitive liposome-nanoparticle (NP) hybrids that can modulate drug release in response to external heating stimulus. These hybrid systems were successfully engineered by the incorporation of gold, sil...

We present an improvement in the electrical properties of silica nanotubes by coating metal nanoparticles on their surfaces. The silica nanotubes are formed from bacterial flagella bio-templates having a tubular structure. Successive depositions of metal nanoparticles on the silica nanotubes are performed through easily functionalized silica surfaces. The results show uniform metal nanoparticle...

Drug delivery systems use different carrier cage-like structures such as bucky ball, therapeutic spheres, carbon nanotube spheres, tiny-tots, smart dots, paramagnetic nanoparticle cages, dendrimers, liposomes etc. The major developments are reported based on the physical properties of these particles such as paramagnetic, immunity, protein profile, transport dynamics, molecular recognition, rec...