In acute iron poisoning, it is necessary for rational management to know whether the plasma iron exceeds the transferrin-binding capacity. A method for the rapid determination of iron in plasma is described whereby this essential information may be obtained in a few minutes. This test will help to differentiate simple iron ingestion from acute iron toxicity so the clinician may have a firmer ba...

BACKGROUND The purpose of this study was to assess the in vivo ability of glucosaminic acid-cobalt (II) chelate to reduce glycemia. METHODS Different concentrations of chelate solution were administrated to mice with diabetes induced by streptozotocin. RESULTS Daily oral administration of chelate solution 0.4 mL at various concentrations (0.32-0.4 g/mL) led to reduction in water intake by t...

Background: Iron overload can cause many complications and damage many organs as well as physiologic functions. Consumption of phetochemicals and flavonoids with iron chelating ability, instead of synthetic iron chelators, can be less harmful and more effective. The aim of this review is to investigate hydrophilic phytochelators in iron overload condition. Methods: In this review, the possible ...

LTHOUGH many substances have been shown to increase iron ahsorption, the mechanism of this action is obscure. Fructose, for example, increases iron absorption in rats, and it has been suggested that its effect depends on its ability to chelate iron.4 We proposed to test this hypothesis, and to in ’estiga e possible relationships between the effects of various metabolic substrates and reducing a...

The Arabidopsis FRO2 gene encodes the low-iron-inducible ferric chelate reductase responsible for reduction of iron at the root surface. Here, we report that FRO2 and IRT1, the major transporter responsible for high-affinity iron uptake from the soil, are coordinately regulated at both the transcriptional and posttranscriptional levels. FRO2 and IRT1 are induced together following the impositio...

Graminaceous plant species acquire soil iron by the release of phytosiderophores and subsequent uptake of iron(III)-phytosiderophore complexes. As plant species differ in their ability for phytosiderophore hydroxylation prior to release, an electrophoretic method was set up to determine whether hydroxylation affects the net charge of iron(III)-phytosiderophore complexes, and thus chelate stabil...

The insolubility of Fe3+ necessitates special mechanisms for iron acquisition in most organisms. Bacteria use siderophores to chelate Fe3+ and iron in heme, hemoglobin, transferrin and lactoferrin, and employ novel mechanisms for receptor-dependent iron transport and iron-regulated gene expression. These mechanisms involve transfer of energy from the cytoplasmic membrane to the outer membrane t...

The 440 fertile eggs, in a completely randomized design were divided into 11 treatments with four replicates and 10 eggs per each replicate. Treatments including: (T1; control; without injection), (T2; injected with 0.3 ml saline 9.0%; sham control), (T3, T4 and T5) 25, 75, 125 ppm Fe-Nano, (T6, T7 and T8) 50, 100, 150 ppm Fe-Nano-Alimet chelate, (T9, T10 and T11) 50, 100, 150 ppm Fe-Aliment ch...

Different root parts with or without increased iron-reducing activities have been studied in iron-deficient and iron-sufficient control sugar beet (Beta vulgaris L. Monohil hybrid). The distal root parts of iron-deficient plants, 0 to 5 mm from the root apex, were capable to reduce Fe(III)-chelates and contained concentrations of flavins near 700 microM, two characteristics absent in the 5 to 1...

In this investigation, attempts were directed to study the inhibitive effects of nitrite and phosphate base inhibitors for the carbon steel alloy samples, which are used in an acid gas treatment process (The SULFIRAN® solution), in Fe-EDTA solution. Electrochemical techniques, i.e. polarization curves and electrochemical impedance spectroscopy (EIS), were used to evaluate the inhibition efficie...